SCHEMBL24910046

SCHEMBL24910046

N#Cc1cc(-c2ccc(C(F)(F)F)o2)c(O)c(C(F)(F)F)c1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
XDH P47989 4/20 0.39
SLC22A12 Q96S37 4/20 0.39
KIF11 P52732 1/20 0.36
TRPV4 Q9HBA0 1/20 0.35
AR P10275 7/20 0.33
P4HB P07237 2/20 0.33
PGR P06401 1/20 0.33
PIK3CA P42336 1/20 0.32
PIK3CG P48736 1/20 0.32
TTR P02766 2/20 0.31
ALB P02768 2/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909337 0.86 XDH (0.36) XDHSLC22A12KIF11TRPV4AR
SCHEMBL24909925 0.75 XDH (0.41) XDHSLC22A12KIF11TRPV4AR
SCHEMBL24909944 0.75 PDK2 (0.37) XDHSLC22A12TRPV4ARPIK3CG
SCHEMBL24909915 0.72 KIF11 (0.41) XDHSLC22A12KIF11TRPV4AR
SCHEMBL24909729 0.71 KDM4E (0.43) XDHSLC22A12KIF11TRPV4AR
SCHEMBL24910055 0.71 PDK2 (0.44) XDHSLC22A12KIF11TRPV4AR
SCHEMBL24909774 0.71 KIF11 (0.40) XDHSLC22A12KIF11TRPV4AR
SCHEMBL24909762 0.70 RXRA (0.46) XDHSLC22A12KIF11TRPV4AR
SCHEMBL24909934 0.70 KIF11 (0.45) XDHSLC22A12KIF11TRPV4AR
SCHEMBL23621183 0.67 TTR (0.64) KIF11TRPV4ARP4HBPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024283-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230024283-A1 HERBICIDAL COMPOUNDS DDT, CBR3, GLRX3 XDH 662/4885SLC22A12 1281/4885KIF11 2192/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.