SCHEMBL24910072

SCHEMBL24910072

Cn1cnc(-c2cc(C#N)cc(C(F)(F)F)c2O)n1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.34
XDH P47989 2/20 0.34
SLC22A12 Q96S37 2/20 0.34
NSD2 O96028 1/20 0.34
CYP2C9 P11712 2/20 0.33
CYP19A1 P11511 2/20 0.33
JAK1 P23458 1/20 0.33
TYK2 P29597 1/20 0.33
STAT3 P40763 1/20 0.33
KCNH2 Q12809 1/20 0.33
TTR P02766 1/20 0.32
ALB P02768 1/20 0.32
P4HB P07237 2/20 0.32
NTRK1 P04629 1/20 0.32
CBLB Q13191 1/20 0.31
CYP11B2 P19099 1/20 0.31
LRRK2 Q5S007 1/20 0.31
GYS1 P13807 1/20 0.31
CTSS P25774 1/20 0.31
CTSK P43235 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909946 0.77 PDE3B (0.38) ARXDHSLC22A12CYP2C9CYP19A1
SCHEMBL24910103 0.75 AR (0.40) ARXDHSLC22A12NSD2CYP2C9
SCHEMBL24909796 0.75 AR (0.34) ARXDHSLC22A12NSD2CYP2C9
SCHEMBL24909416 0.74 CYP11B2 (0.36) ARXDHSLC22A12CYP2C9CYP19A1
SCHEMBL24909793 0.74 HDAC3 (0.39) ARXDHSLC22A12CYP11B2
SCHEMBL24909907 0.73 XDH (0.32) ARXDHSLC22A12NSD2GYS1
SCHEMBL24909738 0.72 CYP11B2 (0.56) ARXDHSLC22A12CYP2C9CYP19A1
SCHEMBL24909746 0.70 GYS1 (0.35) ARXDHSLC22A12CYP2C9CYP19A1
SCHEMBL24909915 0.69 KIF11 (0.41) ARXDHSLC22A12CYP2C9TTR
SCHEMBL31097123 0.68 CRHR1 (0.41) ARXDHSLC22A12CYP19A1GYS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024283-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230024283-A1 HERBICIDAL COMPOUNDS DDT, CBR3, GLRX3 AR 3997/4885XDH 662/4885SLC22A12 1281/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.