SCHEMBL7786554

SCHEMBL7786554

CCCCCC(C)(C)c1cc(CCC(=O)O)ccc1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IAPP P10997 3/20 0.48
KAT8 Q9H7Z6 2/20 0.47
RXRA P19793 1/20 0.44
CYP1A2 P05177 2/20 0.44
CYP3A4 P08684 2/20 0.44
CYP2C8 P10632 2/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2B6 P20813 2/20 0.44
CYP2C19 P33261 2/20 0.44
PPARA Q07869 1/20 0.44
FFAR1 O14842 1/20 0.43
FFAR4 Q5NUL3 1/20 0.43
CNR1 P21554 1/20 0.42
CNR2 P34972 1/20 0.42
TRPV1 Q8NER1 2/20 0.42
HSD17B10 Q99714 1/20 0.42
MEN1 O00255 1/20 0.42
MAPT P10636 1/20 0.42
KMT2A Q03164 1/20 0.42
CYP2E1 P05181 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7796464 0.86 ALDH1A1 (0.49) KAT8PPARATRPV1HSD17B10MAPT
SCHEMBL5929167 0.85 GAA (0.47) RXRAPPARAFFAR1FFAR4MEN1
SCHEMBL2491545 0.85 IAPP (0.46) IAPPKAT8RXRAFFAR1FFAR4
SCHEMBL10879189 0.84 TRPA1 (0.41) IAPPCYP1A2CYP3A4CNR1CNR2
SCHEMBL7792674 0.84 LTA4H (0.47) CYP1A2CYP3A4CYP2C8CYP2C9CYP2B6
SCHEMBL7786552 0.83 RXRA (0.44) IAPPKAT8RXRAFFAR1FFAR4
SCHEMBL3814394 0.83 KDM4E (0.46) IAPPKAT8PPARACNR1CNR2
SCHEMBL10410095 0.82 TRPA1 (0.42) IAPPCYP1A2CYP3A4HSD17B10MEN1
SCHEMBL2911342 0.82 KAT8 (0.43) KAT8CYP3A4PPARACNR1CNR2
SCHEMBL7933763 0.82 APP (0.48) IAPPCYP1A2CYP3A4CYP2C8CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2602300-B1 PHOTOCHROMIC COMPOSITION TOKUYAMA CORP (JP) 2019-06-12 EP disclosed
US-9234984-B2 Photochromic composition TOKUYAMA CORPORATION (JP) 2016-01-12 US disclosed
US-20130215488-A1 Photochromic Composition TOKUYAMA CORPORATION (JP) 2013-08-22 US disclosed
EP-2602300-A1 PHOTOCHROMIC COMPOSITION Tokuyama Corporation (JP) 2013-06-12 EP disclosed
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed