Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 4/20 | 0.50 |
| ▸ | MTOR | P42345 | 3/20 | 0.50 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.35 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | ATF1 | P18846 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24915921 | 0.81 | MTNR1A (0.43) | KDM4EALDH1A1MAPTHPGDJAK2 | |
| SCHEMBL29923902 | 0.80 | HPGDS (0.53) | PIK3CAMTORHPGDSKDM4EALDH1A1 | |
| SCHEMBL24915568 | 0.78 | KDM4E (0.36) | KDM4EALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL24916230 | 0.78 | SCN9A (0.36) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL24916058 | 0.78 | KDM4E (0.50) | KDM4EALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL24915570 | 0.77 | CSNK2A2 (0.39) | KDM4EALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL24915923 | 0.77 | CD38 (0.45) | KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL24915919 | 0.74 | HPGD (0.43) | KDM4EALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL24915573 | 0.72 | KMT2A (0.43) | KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL24915974 | 0.68 | KMT2A (0.40) | MAPTJAK2LMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | PIK3CA 1862/4885MTOR 550/4885HPGDS 2697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.