Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24916059 | 0.85 | POLB (0.41) | ALDH1A1KDM4EPOLBL3MBTL1TSHR | |
| SCHEMBL24916058 | 0.85 | KDM4E (0.50) | HPGDALDH1A1KDM4EGAACDC25B | |
| SCHEMBL24915923 | 0.84 | CD38 (0.45) | HPGDALDH1A1KDM4EPOLBHSD17B10 | |
| SCHEMBL29923598 | 0.84 | HPGD (0.48) | HPGDALDH1A1KDM4EDPP4MAOB | |
| SCHEMBL24916220 | 0.83 | DPP4 (0.45) | HPGDALDH1A1KDM4EDPP4MAOB | |
| SCHEMBL29923655 | 0.82 | ALDH1A1 (0.44) | HPGDALDH1A1KDM4EDPP4MAOB | |
| SCHEMBL24916324 | 0.82 | ALDH1A1 (0.44) | HPGDALDH1A1KDM4EDPP4MAOB | |
| SCHEMBL24915921 | 0.81 | MTNR1A (0.43) | HPGDALDH1A1KDM4EGLAGAA | |
| SCHEMBL24916230 | 0.78 | SCN9A (0.36) | HPGDALDH1A1KDM4EPOLBHSD17B10 | |
| SCHEMBL24915570 | 0.75 | CSNK2A2 (0.39) | HPGDALDH1A1KDM4EPOLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | HPGD 3370/4885ALDH1A1 3815/4885KDM4E 105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.