Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24915597 | 0.80 | BCL2L11 (0.42) | DHFRLMNAHPGDBCL2L11BCL2L1 | |
| SCHEMBL24915593 | 0.80 | LMNA (0.41) | DHFRLMNACYP1A2ALDH1A1HPGD | |
| SCHEMBL24915592 | 0.80 | GRM1 (0.43) | DHFRLMNAGPR3CYP1A2ALDH1A1 | |
| SCHEMBL862361 | 0.79 | PDE3B (0.49) | DHFRGPR3CYP1A2OPRM1OPRD1 | |
| SCHEMBL13870809 | 0.78 | PDE10A (0.44) | DHFRLMNACYP1A2ALDH1A1BCL2L11 | |
| Bromide SCHEMBL5143894 | 0.75 | HPGD (0.53) | LMNACYP1A2ALDH1A1HPGDBCL2L11 | |
| SCHEMBL7516105 | 0.74 | ALDH1A1 (0.48) | DHFRLMNAGPR3CYP1A2OPRM1 | |
| SCHEMBL29923623 | 0.74 | BACE1 (0.47) | DHFRLMNAGPR3CYP1A2OPRM1 | |
| SCHEMBL24916325 | 0.74 | BACE1 (0.47) | DHFRLMNAGPR3CYP1A2OPRM1 | |
| SCHEMBL19009892 | 0.74 | LMNA (0.47) | DHFRLMNACYP1A2ALDH1A1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | DHFR 2700/4885LMNA 3551/4885GPR3 2587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.