Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 3/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24915591 | 0.74 | DHFR (0.48) | LMNAGPR55DHFRCNR2SLC6A2 | |
| SCHEMBL3874965 | 0.71 | KDM4E (0.42) | LMNASMN1; SMN2KDM4EALDH1A1POLB | |
| SCHEMBL18649042 | 0.70 | LMNA (0.35) | LMNADHFRTRPA1CHRM1SLC6A2 | |
| SCHEMBL19009893 | 0.69 | LMNA (0.37) | LMNADHFRSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL25952263 | 0.67 | DHFR (0.36) | LMNAGPR55DHFRKDM4ETDP1 | |
| SCHEMBL24204426 | 0.67 | DHFR (0.36) | LMNAGPR55DHFRCNR2TRPA1 | |
| SCHEMBL12316308 | 0.67 | LMNA (0.33) | LMNADHFRTRPA1CHRM1SLC6A2 | |
| SCHEMBL24858851 | 0.65 | GPR3 (0.43) | SMN1; SMN2KDM4EALDH1A1POLBRAD52 | |
| SCHEMBL20285964 | 0.65 | LMNA (0.40) | LMNADHFRSMN1; SMN2ALDH1A1 | |
| SCHEMBL20412811 | 0.65 | CCR1 (0.37) | LMNASMN1; SMN2KDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170174992-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, COMPOSITION, LIQUID CRYSTAL POLYMERIZATION FILM-KIND THEREOF AND USE THEREOF | JNC CORPORATION (JP) | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174992-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, COMPOSITION, LIQUID CRYSTAL POLYMERIZATION FILM-KIND THEREOF AND USE THEREOF | RCC1, CHRM1, PFN1 | LMNA 432/4885GPR55 3928/4885DHFR 4481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.