Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 7/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | CCNK | O75909 | 1/20 | 0.35 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24916107 | 0.91 | KDM4E (0.38) | CARM1PRMT6KDM4EL3MBTL1HTR1A | |
| SCHEMBL29923797 | 0.91 | KDM4E (0.38) | CARM1PRMT6KDM4EL3MBTL1HTR1A | |
| SCHEMBL24916497 | 0.89 | KDM4E (0.41) | CARM1PRMT6KDM4EL3MBTL1HTR1A | |
| SCHEMBL24916030 | 0.85 | TLR9 (0.37) | RAB9AKDM4EL3MBTL1SLC6A4GSK3B | |
| SCHEMBL29923662 | 0.80 | SMN1; SMN2 (0.48) | RAB9AKDM4EL3MBTL1GAAMAPT | |
| SCHEMBL24915662 | 0.80 | SMN1; SMN2 (0.48) | RAB9AKDM4EL3MBTL1GAAMAPT | |
| SCHEMBL29923354 | 0.79 | ALDH1A1 (0.40) | RAB9AKDM4EL3MBTL1HTR1ASLC6A4 | |
| SCHEMBL24916141 | 0.79 | ALDH1A1 (0.40) | RAB9AKDM4EL3MBTL1HTR1ASLC6A4 | |
| SCHEMBL24915807 | 0.78 | KDM4E (0.38) | RAB9AKDM4EL3MBTL1HTR1AGAA | |
| SCHEMBL29923349 | 0.78 | KDM4E (0.38) | RAB9AKDM4EL3MBTL1HTR1AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | CARM1 448/4885PRMT6 312/4885RAB9A 1682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.