Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24916324 | 1.00 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDDPP4CDC25B | |
| SCHEMBL29923598 | 0.86 | HPGD (0.48) | ALDH1A1KDM4EHPGDDPP4CDC25B | |
| SCHEMBL29923210 | 0.84 | ALDH1A1 (0.42) | ALDH1A1KDM4ESMN1; SMN2L3MBTL1MAOB | |
| SCHEMBL24915691 | 0.84 | ALDH1A1 (0.42) | ALDH1A1KDM4ESMN1; SMN2L3MBTL1MAOB | |
| SCHEMBL24915919 | 0.82 | HPGD (0.43) | ALDH1A1KDM4EHPGDDPP4CDC25B | |
| SCHEMBL24915732 | 0.82 | DPP4 (0.46) | ALDH1A1KDM4EHPGDDPP4CDC25B | |
| SCHEMBL29923458 | 0.82 | DPP4 (0.46) | ALDH1A1KDM4EHPGDDPP4CDC25B | |
| SCHEMBL19783054 | 0.74 | HPGD (0.48) | ALDH1A1KDM4EHPGDDPP4CDC25B | |
| SCHEMBL22750299 | 0.73 | CRHR1 (0.47) | ALDH1A1CYP3A4SMN1; SMN2GAAPOLB | |
| SCHEMBL29923906 | 0.73 | CRHR1 (0.47) | ALDH1A1CYP3A4SMN1; SMN2GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |