Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24915919 | 0.85 | HPGD (0.43) | POLBL3MBTL1KDM4EALDH1A1TSHR | |
| SCHEMBL24915920 | 0.84 | L3MBTL1 (0.37) | L3MBTL1KDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL24916409 | 0.82 | GABRA1 (0.43) | L3MBTL1KDM4EALDH1A1KMT2ATSHR | |
| SCHEMBL29923210 | 0.82 | ALDH1A1 (0.42) | L3MBTL1KDM4EALDH1A1KMT2ATSHR | |
| SCHEMBL24915691 | 0.82 | ALDH1A1 (0.42) | L3MBTL1KDM4EALDH1A1KMT2ATSHR | |
| SCHEMBL24915922 | 0.80 | MEN1 (0.40) | L3MBTL1KDM4EALDH1A1KMT2ATSHR | |
| SCHEMBL24915926 | 0.77 | TLR9 (0.42) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL24916053 | 0.76 | DHFR (0.43) | POLBL3MBTL1KDM4EMAPT | |
| SCHEMBL24916056 | 0.74 | KDM4E (0.34) | POLBL3MBTL1KDM4EALDH1A1MAPT | |
| SCHEMBL22766603 | 0.70 | GABRA1 (0.47) | L3MBTL1KDM4EALDH1A1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | POLB 3227/4885L3MBTL1 1214/4885KDM4E 105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.