Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 10/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 10/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 10/20 | 0.37 |
| ▸ | HTR1D | P28221 | 5/20 | 0.34 |
| ▸ | HTR1B | P28222 | 5/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | HTR1F | P30939 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR1E | P28566 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24916006 | 0.81 | TLR9 (0.42) | TLR9TLR8TLR7HTR1DHTR1B | |
| SCHEMBL24915960 | 0.79 | HTR1A (0.41) | TLR9TLR8TLR7HTR1AHTR2A | |
| SCHEMBL24915530 | 0.77 | HTR7 (0.42) | — | |
| SCHEMBL22253420 | 0.74 | NPC1 (0.36) | CYP3A4HTR1AHTR2AHTR2C | |
| SCHEMBL24915529 | 0.73 | HTR7 (0.42) | — | |
| SCHEMBL24915952 | 0.71 | PIK3CA (0.37) | — | |
| SCHEMBL24916036 | 0.70 | KDM4E (0.36) | — | |
| SCHEMBL24916039 | 0.70 | NOS3 (0.36) | HTR1DHTR1BHTR1A | |
| SCHEMBL24915647 | 0.70 | NOS3 (0.33) | — | |
| SCHEMBL24916426 | 0.69 | HPGD (0.35) | CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | TLR9 4379/4885TLR8 4298/4885TLR7 4346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.