Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24916013 | 0.88 | MAP4K4 (0.40) | L3MBTL1KMT2AMEN1EGLN1 | |
| SCHEMBL24915532 | 0.87 | LMNA (0.48) | TSHRRAB9ALMNAMAPTNPC1 | |
| SCHEMBL24915997 | 0.87 | GPR52 (0.39) | KMT2AMEN1MAPTEGLN1 | |
| SCHEMBL24916021 | 0.85 | KMT2A (0.45) | RAB9AKMT2AMEN1LMNANPC1 | |
| SCHEMBL24916033 | 0.84 | RAB9A (0.43) | RAB9AKMT2ACYP1A2LMNANPC1 | |
| SCHEMBL24916193 | 0.83 | CSF1R (0.38) | KMT2AMAPTNPC1SMN1; SMN2GAA | |
| SCHEMBL24915849 | 0.82 | PLK1 (0.37) | L3MBTL1RAB9ACYP1A2LMNANPC1 | |
| SCHEMBL24916012 | 0.82 | EGLN1 (0.34) | KMT2AMEN1EGLN1 | |
| SCHEMBL24915710 | 0.82 | KDM5A (0.40) | KMT2AMAPTNPC1SMN1; SMN2GAA | |
| SCHEMBL29923470 | 0.78 | EGLN1 (0.51) | NAAAL3MBTL1EPHX2RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | NAAA 2870/4885TSHR 4798/4885L3MBTL1 1214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.