Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 3/20 | 0.31 |
| ▸ | LPL | P06858 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24920105 | 0.80 | PRMT5 (0.34) | PRMT5WDR77CSF1RIDO1TDO2 | |
| SCHEMBL24920087 | 0.75 | LIPG (0.46) | LPLLIPG | |
| SCHEMBL24920074 | 0.71 | IDO1 (0.34) | PRMT5WDR77IDO1TDO2 | |
| SCHEMBL11000 | 0.70 | ATM (0.41) | PRMT5WDR77CSF1RLPLLIPG | |
| SCHEMBL15912503 | 0.69 | LPL (0.42) | PRMT5WDR77CSF1RLPLLIPG | |
| SCHEMBL31468044 | 0.69 | LPL (0.45) | PRMT5WDR77CSF1RIDO1TDO2 | |
| SCHEMBL30665809 | 0.69 | LPL (0.39) | PRMT5WDR77CSF1RLPLLIPG | |
| SCHEMBL30665811 | 0.69 | LPL (0.39) | PRMT5WDR77CSF1RLPLLIPG | |
| SCHEMBL24920082 | 0.68 | LPL (0.31) | LPLLIPG | |
| SCHEMBL24920081 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023004138-A1 | AGONISTS OF TYRO3 AS PROTECTION AGAINST PODOCYTE INJURY IN KIDNEY GLOMERULAR DISEASE | DAS BHASKAR (US) | 2023-01-26 | — | — | WO | disclosed |