SCHEMBL24920082

SCHEMBL24920082

CC1SC(c2ccc3ccc(B4OC(C)(C)C(C)(C)O4)cn23)=NC1=O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LPL P06858 3/20 0.31
LIPG Q9Y5X9 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24920081 0.84
SCHEMBL24920087 0.78 LIPG (0.46) LPLLIPG
SCHEMBL24920105 0.69 PRMT5 (0.34) LPLLIPG
SCHEMBL24920106 0.68 PRMT5 (0.36) LPLLIPG
SCHEMBL28498721 0.67 LPL (0.38) LPLLIPG
SCHEMBL24920100 0.67 SNCA (0.33)
SCHEMBL13349614 0.65 LPL (0.36) LPLLIPG
SCHEMBL28572034 0.64 LIPG (0.39) LPLLIPG
SCHEMBL24920078 0.64 SNCA (0.32)
SCHEMBL31731068 0.63 LPL (0.42) LPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023004138-A1 AGONISTS OF TYRO3 AS PROTECTION AGAINST PODOCYTE INJURY IN KIDNEY GLOMERULAR DISEASE DAS BHASKAR (US) 2023-01-26 WO disclosed