Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29325624 | 0.90 | HRH1 (0.36) | MEN1CYP2D6HRH3HRH1HRH2 | |
| SCHEMBL19977411 | 0.87 | DRD2 (0.37) | MEN1HTR4CYP2D6HRH3CYP1A2 | |
| SCHEMBL24920438 | 0.84 | DRD2 (0.34) | MEN1HTR4CYP2D6HRH3CYP1A2 | |
| SCHEMBL24920953 | 0.83 | SIGMAR1 (0.37) | SIGMAR1 | |
| SCHEMBL24920944 | 0.83 | SIGMAR1 (0.37) | SIGMAR1 | |
| SCHEMBL24921699 | 0.81 | DRD2 (0.34) | MEN1HTR4CYP2D6HRH3CYP1A2 | |
| SCHEMBL22565121 | 0.80 | NCF1 (0.41) | SIGMAR1ACHEOPRM1OPRK1OPRL1 | |
| SCHEMBL24940877 | 0.80 | CHRM5 (0.39) | SIGMAR1ACHEOPRM1OPRK1OPRL1 | |
| SCHEMBL24921700 | 0.80 | HRH1 (0.38) | MEN1HTR4CYP2D6CYP3A4HRH3 | |
| SCHEMBL27267884 | 0.79 | ACHE (0.37) | HRH3SIGMAR1ACHEOPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |