Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24921040 | 0.98 | AOC3 (0.44) | MAPTAOC3ACHEKMT2AMEN1 | |
| SCHEMBL24921023 | 0.95 | AOC3 (0.44) | MAPTAOC3ACHEKMT2ACA12 | |
| SCHEMBL24920536 | 0.86 | ACHE (0.48) | AOC3ACHEKMT2AMEN1HTT | |
| SCHEMBL24920548 | 0.86 | ACHE (0.48) | AOC3ACHEKMT2AMEN1CA12 | |
| SCHEMBL24920523 | 0.85 | ADRB1 (0.51) | AOC3ACHEHPGD | |
| SCHEMBL15599258 | 0.82 | ACHE (0.46) | ACHECA12CA1CA2CA9 | |
| SCHEMBL21715629 | 0.80 | ACHE (0.47) | MAPTACHEKMT2AMEN1CCNT1 | |
| SCHEMBL24921022 | 0.80 | AOC3 (0.38) | AOC3ACHERXRAGRIN1GRIN2B | |
| SCHEMBL24921790 | 0.79 | AOC3 (0.39) | AOC3ACHERXRAGRIN1GRIN2B | |
| SCHEMBL24921025 | 0.79 | RXRA (0.39) | AOC3RXRAGRIN1GRIN2BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |