Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | IDH1 | O75874 | 2/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20745993 | 0.78 | PARP1 (0.35) | L3MBTL1IDH1ALDH1A1HPGDPARP1 | |
| SCHEMBL24920544 | 0.77 | MAP4K1 (0.43) | RXRAGRIN1GRIN2BIDH1AOC3 | |
| SCHEMBL24921040 | 0.77 | AOC3 (0.44) | RXRAGRIN1GRIN2BAOC3PDE10A | |
| SCHEMBL24921023 | 0.77 | AOC3 (0.44) | RXRAGRIN1GRIN2BAOC3KMT2A | |
| SCHEMBL24920520 | 0.76 | MAPT (0.46) | RXRAGRIN1GRIN2BAOC3HPGD | |
| SCHEMBL24920539 | 0.72 | PIK3C3 (0.38) | RXRAGRIN1GRIN2BIDH1AOC3 | |
| SCHEMBL24920548 | 0.71 | ACHE (0.48) | AOC3ALDH1A1MEN1KMT2A | |
| SCHEMBL24920536 | 0.71 | ACHE (0.48) | L3MBTL1AOC3ALDH1A1HPGDHTT | |
| SCHEMBL24921027 | 0.71 | RXRA (0.37) | RXRAGRIN1GRIN2BAOC3NPC1 | |
| SCHEMBL22320524 | 0.71 | CRBN (0.50) | L3MBTL1IDH1ALDH1A1HPGDPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |