Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24920831 | 0.77 | LRRK2 (0.36) | PDE10A | |
| SCHEMBL24920864 | 0.74 | MAPT (0.39) | ALDH1A1 | |
| SCHEMBL24920807 | 0.74 | LRRK2 (0.36) | CYP1A2MEN1ALDH1A1GLACYP3A4 | |
| SCHEMBL24921528 | 0.73 | FTO (0.37) | PDE10A | |
| SCHEMBL24920896 | 0.72 | CYP1A2 (0.31) | CYP1A2MEN1ALDH1A1GLACYP3A4 | |
| SCHEMBL24920791 | 0.72 | GUCY1B2 (0.35) | PDE10AALDH1A1GLAKMT2AHSD17B10 | |
| SCHEMBL24921585 | 0.72 | PDE10A (0.35) | PDE10A | |
| SCHEMBL24920776 | 0.71 | L3MBTL1 (0.36) | ALDH1A1HSD17B10 | |
| SCHEMBL24921964 | 0.69 | PDE10A (0.31) | PDE10A | |
| SCHEMBL24920818 | 0.69 | CYP1A2 (0.33) | CYP1A2MEN1ALDH1A1GLACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |