Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24920776 | 0.77 | L3MBTL1 (0.36) | HDAC1HDAC6HDAC5HSD17B10ALDH1A1 | |
| SCHEMBL24920793 | 0.73 | GUCY1B2 (0.40) | KMT2APPARA | |
| SCHEMBL24921552 | 0.73 | FTO (0.37) | PPARA | |
| SCHEMBL24921572 | 0.72 | PDK2 (0.34) | HDAC1HDAC6HDAC5 | |
| SCHEMBL24920896 | 0.72 | CYP1A2 (0.31) | CYP1A2HSD17B10ALDH1A1CYP3A4MEN1 | |
| SCHEMBL24920831 | 0.71 | LRRK2 (0.36) | HDAC1HDAC6HDAC5 | |
| SCHEMBL24920864 | 0.71 | MAPT (0.39) | ALDH1A1TSHRMAPK1HPGD | |
| SCHEMBL24921985 | 0.69 | CNR2 (0.33) | — | |
| SCHEMBL24920816 | 0.69 | PDE10A (0.31) | CYP1A2HSD17B10ALDH1A1CYP3A4MEN1 | |
| SCHEMBL21905028 | 0.68 | CYP1A2 (0.37) | CYP1A2HSD17B10ALDH1A1CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |