Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 2/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.35 |
| ▸ | TTK | P33981 | 1/20 | 0.35 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24656018 | 0.80 | CA1 (0.48) | CA1CA2ALDH1A1GAAMEN1 | |
| SCHEMBL22949457 | 0.80 | CA1 (0.53) | CA1CA2MAPTCASP1ALDH1A1 | |
| SCHEMBL25449418 | 0.80 | CA2 (0.39) | CA1CA2MAPTCASP1AURKA | |
| SCHEMBL20843988 | 0.78 | CA1 (0.47) | CA1CA2ALDH1A1GAAMEN1 | |
| SCHEMBL21719145 | 0.78 | CA1 (0.47) | CA1CA2ALDH1A1GAAHPGD | |
| SCHEMBL12401753 | 0.78 | LMNA (0.43) | CA1CA2MAPTCASP1AURKA | |
| SCHEMBL18501252 | 0.78 | ALOX5AP (0.35) | CA1CA2MAPTCASP1AURKA | |
| SCHEMBL9885336 | 0.76 | CYP1A2 (0.42) | AURKAAURKBMEN1KMT2AHPGD | |
| SCHEMBL7321441 | 0.72 | MAPT (0.39) | MAPTCASP1AURKAAURKBTTK | |
| SCHEMBL2655524 | 0.72 | MAPT (0.39) | MAPTCASP1AURKAAURKBTTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230035796-A1 | CURCUMINOIDS, ANALOGS THEREOF, AND METHODS OF MAKING THE SAME | WISYS TECHNOLOGY FOUNDATION, INC. | 2023-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230035796-A1 | CURCUMINOIDS, ANALOGS THEREOF, AND METHODS OF MAKING THE SAME | PTGES, ALOX5, ALOX15 | CA1 2097/4885CA2 3557/4885MAPT 1912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.