SCHEMBL24923136

SCHEMBL24923136

c1ccc2c(c1)oc1ccc3c(c4ccccc4n3-c3ccc(-c4ccc(-c5ccc6sc7ccccc7c6c5)cc4)cc3)c12

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 1/20 0.33
PLA2G4A P47712 1/20 0.33
KDM4E B2RXH2 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
GPR3 P46089 1/20 0.31
CASP3 P42574 1/20 0.30
SENP7 Q9BQF6 1/20 0.30
SENP6 Q9GZR1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17126152 0.92 PLA2G2A (0.33) PLA2G2APLA2G4A
SCHEMBL17126134 0.92 PLA2G2A (0.33) PLA2G2APLA2G4A
SCHEMBL17246138 0.91 GPR3 (0.34) KDM4EATML3MBTL1GPR3
SCHEMBL26508541 0.91 AHR (0.30) KDM4E
SCHEMBL24923142 0.90 KDM4E (0.33) PLA2G2APLA2G4AKDM4EATML3MBTL1
SCHEMBL25775511 0.89 MAPT (0.32) PLA2G2APLA2G4AKDM4EATML3MBTL1
SCHEMBL16811598 0.89 PLA2G2A (0.32) PLA2G2APLA2G4A
SCHEMBL11987378 0.89 KDM4E (0.36) PLA2G2APLA2G4AKDM4EATML3MBTL1
SCHEMBL20698528 0.88 ALOX5 (0.38)
SCHEMBL24230923 0.87 ATM (0.44) KDM4EATML3MBTL1GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230033529-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-02-02 US disclosed
US-20230027888-A1 ORGANIC ELECTROLUMINESCENT DEVICE, ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE, ELECTRONIC DEVICE AND COMPOUND IDEMITSU KOSAN CO.,LTD. (JP) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230027888-A1 ORGANIC ELECTROLUMINESCENT DEVICE, ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE, ELECTRONIC DEVICE AND COMPOUND HTR1D, EHD1, HTR3D PLA2G2A 2503/4885PLA2G4A 3240/4885KDM4E 3361/4885
US-20230033529-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE LEF1, L1CAM, RAP1A PLA2G2A 2978/4885PLA2G4A 3778/4885KDM4E 3096/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.