SCHEMBL24923487

SCHEMBL24923487

c1ccc2c(c1)oc1c2ccc2c3ccccc3n(-c3ccc(-c4ccc(-c5ccc6c(c5)sc5ccccc56)cc4)cc3)c21

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ESR2 Q92731 1/20 0.33
ALOX5 P09917 1/20 0.33
KDM4E B2RXH2 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
GPR3 P46089 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17246082 1.00 ALDH1A1 (0.33) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL17246081 0.94 ESR2 (0.32) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL24923051 0.94 ESR2 (0.32) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL24676301 0.92 KDM4E (0.31) ESR2ALOX5KDM4EATML3MBTL1
SCHEMBL17246024 0.91 ALDH1A1 (0.36) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL17246020 0.87 ESR2 (0.34) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL24810813 0.87 ALOX5 (0.33) ALDH1A1ESR2ALOX5
SCHEMBL17126137 0.87 PLA2G2A (0.30)
SCHEMBL17126149 0.87 PLA2G2A (0.30)
SCHEMBL9889953 0.87 KDM4E (0.41) ALDH1A1MAPTHPGDALOX5KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230033529-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-02-02 US disclosed
US-20230027888-A1 ORGANIC ELECTROLUMINESCENT DEVICE, ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE, ELECTRONIC DEVICE AND COMPOUND IDEMITSU KOSAN CO.,LTD. (JP) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230027888-A1 ORGANIC ELECTROLUMINESCENT DEVICE, ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE, ELECTRONIC DEVICE AND COMPOUND HTR1D, EHD1, HTR3D ALDH1A1 300/4885MAPT 2184/4885HPGD 1934/4885
US-20230033529-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE LEF1, L1CAM, RAP1A ALDH1A1 42/4885MAPT 3231/4885HPGD 4336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.