Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4686720 | 1.00 | KMT2A (0.54) | KMT2AALDH1A1L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL2445407 | 1.00 | KMT2A (0.54) | KMT2AALDH1A1L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL29936503 | 0.92 | ASIC1 (0.54) | KMT2AALDH1A1L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL29936120 | 0.92 | ASIC1 (0.54) | KMT2AALDH1A1L3MBTL1KDM4ESMN1; SMN2 | |
| Benzaldehyde Oxime SCHEMBL266504 | 0.85 | — | — | |
| Benzaldehyde Oxime SCHEMBL309201 | 0.85 | — | — | |
| Benzaldehyde Oxime SCHEMBL220641 | 0.85 | — | — | |
| Benzaldehyde Oxime SCHEMBL9761423 | 0.82 | L3MBTL1 (0.57) | KMT2AALDH1A1L3MBTL1KDM4ESMN1; SMN2 | |
| Benzaldehyde Oxime SCHEMBL10645128 | 0.82 | L3MBTL1 (0.57) | KMT2AALDH1A1L3MBTL1KDM4ESMN1; SMN2 | |
| Benzaldehyde Oxime SCHEMBL4607427 | 0.82 | L3MBTL1 (0.57) | KMT2AALDH1A1L3MBTL1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107488090-B | Efficient catalytic asymmetric preparation method of N-cyclopropyl nitrone compound | 东北师范大学 | 2020-06-02 | — | — | CN | claimed |
| WO-1998005630-A1 | PROCESS FOR THE PREPARATION OF ORGANIC NITRILES | ALLIEDSIGNAL INC. (US) | 1998-02-12 | — | — | WO | claimed |
| US-12570675-B2 | Boronic acid compounds | LG CHEM, LTD. (KR) | 2026-03-10 | — | — | US | disclosed |
| US-20240101579-A1 | BORONIC ACID COMPOUNDS | LG CHEM, LTD. (KR) | 2024-03-28 | — | — | US | disclosed |
| EP-4242213-A1 | BORONIC ACID COMPOUND | Lg Chem, Ltd. (KR) | 2023-09-13 | — | — | EP | disclosed |
| CN-116568310-A | Boric acid compounds | 株式会社LG化学 | 2023-08-08 | — | — | CN | disclosed |
| WO-2022123530-A1 | BORONIC ACID COMPOUND | 주식회사 엘지화학 | 2022-06-16 | — | — | WO | disclosed |
| CN-107488090-B | Efficient catalytic asymmetric preparation method of N-cyclopropyl nitrone compound | 东北师范大学 | 2020-06-02 | — | — | CN | disclosed |
| US-20190135765-A1 | NOVEL PYRIMIDINE-4-CARBOXYLIC ACID DERIVATIVE HAVING ANTICANCER ACTIVITY | INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) | 2019-05-09 | — | — | US | disclosed |
| US-20190135765-A1 | NOVEL PYRIMIDINE-4-CARBOXYLIC ACID DERIVATIVE HAVING ANTICANCER ACTIVITY | INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) | 2019-05-09 | — | — | US | disclosed |
| WO-2018170167-A1 | FARNESOID X RECEPTOR AGONISTS AND USES THEREOF | METACRINE, INC. (US) | 2018-09-20 | — | — | WO | disclosed |
| US-5972959-A | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0708098-B1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1999-03-03 | — | — | EP | disclosed |
| US-5780490-A | A O-(2,4-OXA(OR THIA)ZOLIDINYL)PHENYLOXY(OR THIO OR AMINO) ALKYLOXIME; ALDOSE REDUCTASE INHIBITORS; ANTIDIABETIC AND -HYPOGLYCEMIC AGENTS; LIVER, SKIN AND UROGENITAL DISORDERS | SANKYO COMPANY, LIMITED (JP) | 1998-07-14 | — | — | US | disclosed |
| WO-1998005630-A1 | PROCESS FOR THE PREPARATION OF ORGANIC NITRILES | ALLIEDSIGNAL INC. (US) | 1998-02-12 | — | — | WO | disclosed |
| US-5703096-A | ANTIDIABETIC AGENTS; ALDOSE REDUCTASE INHIBITOR | SANKYO COMPANY, LIMITED (JP) | 1997-12-30 | — | — | US | disclosed |
| CN-1143639-A | Oxime derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1997-02-26 | — | — | CN | disclosed |
| EP-0708098-A1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1996-04-24 | — | — | EP | disclosed |
| EP-0559888-A1 | THERMOSETTING POLYESTER PLASTIC COMPOSITIONS CONTAINING BLOCKED POLYISOCYANATE AND ISOCYANATE-REACTIVE MATERIAL | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1993-09-15 | — | — | EP | disclosed |
| WO-1993007216-A1 | THERMOSETTING POLYESTER PLASTIC COMPOSITIONS CONTAINING BLOCKED POLYISOCYANATE AND ISOCYANATE-REACTIVE MATERIAL | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1993-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12570675-B2 | Boronic acid compounds | PSMB6, PSMB3, PSMB2 | KMT2A 2072/4885ALDH1A1 3621/4885L3MBTL1 393/4885 |
| US-20240101579-A1 | BORONIC ACID COMPOUNDS | PSMB11, PSMB1, BACH1 | KMT2A 1197/4885ALDH1A1 2005/4885L3MBTL1 599/4885 |
| US-20190135765-A1 | NOVEL PYRIMIDINE-4-CARBOXYLIC ACID DERIVATIVE HAVING ANTICANCER ACTIVITY | DPYD, TYMS, TYMP | KMT2A 2256/4885ALDH1A1 153/4885L3MBTL1 2361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.