Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.38 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | OGA | O60502 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29775988 | 0.88 | KDM4E (0.39) | NPSR1KDM4EPOLBTRPV1TRPV3 | |
| SCHEMBL29776077 | 0.88 | NPSR1 (0.39) | NPSR1KDM4EPOLBTRPV1TRPV3 | |
| SCHEMBL23212679 | 0.88 | KDM4E (0.39) | NPSR1KDM4EPOLBTRPV1TRPV3 | |
| SCHEMBL23213901 | 0.88 | NPSR1 (0.39) | NPSR1KDM4EPOLBTRPV1TRPV3 | |
| SCHEMBL23329670 | 0.79 | TGFBR1 (0.36) | TRPV3SYK | |
| SCHEMBL12277748 | 0.79 | KIF11 (0.46) | TRPV1TRPV3KIF11 | |
| SCHEMBL29776111 | 0.78 | LIPE (0.38) | NPSR1KDM4ETRPV1SYKL3MBTL1 | |
| SCHEMBL30010484 | 0.77 | TRPV1 (0.35) | KDM4ETRPV1TRPV3SYKL3MBTL1 | |
| SCHEMBL23213969 | 0.77 | TRPV1 (0.35) | KDM4ETRPV1TRPV3SYKL3MBTL1 | |
| SCHEMBL23329668 | 0.76 | GBA1 (0.33) | KDM4EL3MBTL1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230023326-A1 | HETEROARYL-SUBSTITUTED PYRAZINE DERIVATIVES AS PESTICIDES | ELANCO ANIMAL HEALTH GMBH (DE) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230023326-A1 | HETEROARYL-SUBSTITUTED PYRAZINE DERIVATIVES AS PESTICIDES | DDT, PRXL2A, CAT | NPSR1 253/4885KDM4E 2574/4885POLB 4537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.