Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29873923 | 0.98 | KDM4E (0.36) | KDM4EALDH1A1CYP3A4GABRB3OPRD1 | |
| SCHEMBL6690925 | 0.85 | KDM4E (0.43) | KDM4EALDH1A1CYP3A4GABRB3OPRD1 | |
| SCHEMBL24938561 | 0.84 | ADAMTS5 (0.34) | KDM4EALDH1A1CYP3A4GABRB3OPRD1 | |
| SCHEMBL23354823 | 0.82 | ADAMTS5 (0.40) | KDM4EALDH1A1CYP3A4GABRB3OPRD1 | |
| Hydrochloric Acid SCHEMBL23354793 | 0.82 | ADAMTS5 (0.34) | KDM4EALDH1A1CYP3A4GABRB3OPRD1 | |
| SCHEMBL6694378 | 0.81 | KDM4E (0.41) | KDM4EALDH1A1CYP3A4GABRB3OPRD1 | |
| SCHEMBL6692937 | 0.81 | KDM4E (0.37) | KDM4EALDH1A1CYP3A4GABRB3OPRD1 | |
| Hydrochloric Acid SCHEMBL31676880 | 0.81 | ADAMTS5 (0.39) | KDM4EALDH1A1CYP3A4GABRB3OPRD1 | |
| Hydrochloric Acid SCHEMBL23353975 | 0.81 | ADAMTS5 (0.39) | KDM4EALDH1A1CYP3A4GABRB3OPRD1 | |
| SCHEMBL6699914 | 0.79 | KDM4E (0.39) | KDM4EALDH1A1CYP3A4GABRB3OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230027985-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-01-26 | — | — | US | disclosed |
| US-20230027346-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230027985-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | ADAMTS7, MMP7, ADAMTS1 | KDM4E 2923/4885ALDH1A1 2009/4885CYP3A4 3940/4885 |
| US-20230027346-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | ADAMTS7, MMP7, ADAM17 | KDM4E 3062/4885ALDH1A1 3828/4885CYP3A4 3418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.