SCHEMBL24928

SCHEMBL24928

Nc1ccc(O)cc1[N+](=O)[O-]

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.64
TDP1 Q9NUW8 4/20 0.64
ALOX15 P16050 3/20 0.64
MEN1 O00255 2/20 0.64
POLB P06746 2/20 0.64
KMT2A Q03164 2/20 0.64
CYP3A4 P08684 2/20 0.64
MAPT P10636 1/20 0.64
TSHR P16473 4/20 0.60
LMNA P02545 1/20 0.59
GPR35 Q9HC97 3/20 0.53
MAPK1 P28482 2/20 0.50
GAA P10253 1/20 0.50
THRB P10828 1/20 0.50
PKM P14618 1/20 0.50
HSD17B10 Q99714 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
TP53 P04637 1/20 0.47
HPGD P15428 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29622134 1.00 ALDH1A1 (0.64) ALDH1A1TDP1ALOX15MEN1POLB
SCHEMBL8664793 0.87 GPR35 (0.78) ALDH1A1TDP1ALOX15MEN1POLB
2-Amino-4-Nitrophenol SCHEMBL6003570 0.87 GAA (0.75) ALDH1A1TDP1ALOX15MEN1POLB
Di(Hydroxyethyl)Ether SCHEMBL7082245 0.85 TDP1 (0.49) ALDH1A1TDP1ALOX15MEN1POLB
SCHEMBL27864753 0.85 TDP1 (0.79) ALDH1A1TDP1ALOX15MEN1POLB
SCHEMBL6001825 0.84 TDP1 (0.47) ALDH1A1TDP1ALOX15MEN1POLB
SCHEMBL3742310 0.83 TDP1 (0.64) ALDH1A1TDP1ALOX15MEN1POLB
SCHEMBL14547836 0.81 TDP1 (0.41) ALDH1A1TDP1ALOX15MEN1POLB
SCHEMBL11714590 0.81 LMNA (0.66) ALDH1A1TDP1ALOX15MEN1POLB
SCHEMBL213758 0.80 TSHR (0.56) ALDH1A1ALOX15CYP3A4TSHRGPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7963 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3723864-B1 THICKENED ONE-COMPONENT HAIR TONER HENKEL AG & CO KGAA (DE) 2026-01-14 EP claimed
US-12364660-B2 Granulated hair dye composition WELLA GERMANY GMBH (DE) 2025-07-22 US claimed
CN-115980205-B Quantitative and/or qualitative method for simultaneously measuring 54 hair dyes in hair dye product 江苏省食品药品监督检验研究院 2025-04-22 CN claimed
EP-3873407-B1 TWO-COMPONENT SYSTEM FOR ARTIFICIAL HAIR DYEING HENKEL AG & CO KGAA (DE) 2025-04-09 EP claimed
CN-119708700-A Weather-resistant PP composite material and preparation method thereof 江西旭联新材料有限责任公司 2025-03-28 CN claimed
WO-2025061335-A1 METHOD FOR DYEING KERATIN FIBRES, COMPRISING THE APPLICATION OF AN OXIDATIVE PRE-TREATMENT AGENT AND A DYE COMPRISING DIRECT DYES HENKEL AG & CO. KGAA (DE) 2025-03-27 WO claimed
WO-2025047878-A1 HAIR DYE COMPOSITION COMPRISING BLUE DYES, UREA AND A CATIONIC SURFACTANT HENKEL AG & CO. KGAA (DE) 2025-03-06 WO claimed
US-20240423887-A1 COMPOSITION COMPRISING A DYE AND INORGANIC ALKALIZING AGENT KAO CORPORATION (JP) 2024-12-26 US claimed
US-20240350386-A1 Hair Coloring Compositions Comprising Hydroxyalkyl Amines As Alkalising Agents WELLA GERMANY GMBH (DE) 2024-10-24 US claimed
EP-4247323-B1 GRANULATED HAIR DYE COMPOSITION WELLA GERMANY GMBH (DE) 2024-09-04 EP claimed
EP-0480829-B1 Hair dyeing composition containing anthraquinones OREAL (FR) 1994-04-06 EP claimed
US-5226924-A 1,4-DI(MONO- OR POLY) HYDROXYALKYLAMINO-9,10-ANTHRAQUINONES FOR DYEING HUMAN KERATINOUS FIBRES, COSMETIC COMPOSITION CONTAINING THEM IN COMBINATION WITH AZO AND NITROBENZENE DYES, AND HAIR-DYEING PROCESS USING THEM L'OREAL (FR) 1993-07-13 US claimed
EP-0480829-A1 Hair dyeing composition containing anthraquinones L'OREAL (FR) 1992-04-15 EP claimed
US-4935032-A DIRECT NITROBENZENE DYE L'OREAL (FR) 1990-06-19 US claimed
US-4563188-A SHADES OF GREEN L'OREAL (FR) 1986-01-07 US claimed
US-4494953-A 2,4-Dihydroxydiphenylamines and hair dyeing compositions and method L'OREAL (FR) 1985-01-22 US claimed
US-4333730-A HAIR DYES SOCIETE ANONYME DITE: L'OREAL (FR) 1982-06-08 US claimed
US-4324553-A OXIDATION COLOR DYES L'OREAL (FR) 1982-04-13 US claimed
US-4323360-A Dyeing compositions for hair which contain 2,4-diamino-butoxybenzene and/or a salt thereof as the coupling agent L'OREAL (FR) 1982-04-06 US claimed
US-4125601-A Substituted nitroaminophenols, process for their preparation and dyeing compositions in which they are present L'OREAL (FR) 1978-11-14 US claimed