Sugi Predict

Sugi Predict / Compounds / 2-Amino-4-Nitrophenol

2-Amino-4-Nitrophenol

2-Amino-4-Nitrophenol

SCHEMBL6003570

Nc1cc([N+](=O)[O-])ccc1O.Nc1ccc(O)cc1[N+](=O)[O-]

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 2/20 0.75
▸ THRB P10828 1/20 0.75
▸ TDP1 Q9NUW8 7/20 0.64
▸ ALDH1A1 P00352 6/20 0.57
▸ TSHR P16473 4/20 0.57
▸ GPR35 Q9HC97 3/20 0.57
▸ MAPK1 P28482 2/20 0.57
▸ TP53 P04637 1/20 0.57
▸ HPGD P15428 1/20 0.57
▸ SMN1; SMN2 Q16637 1/20 0.57
▸ MEN1 O00255 2/20 0.51
▸ MAPT P10636 2/20 0.51
▸ KMT2A Q03164 2/20 0.51
▸ KDM4E B2RXH2 1/20 0.51
▸ GFER P55789 1/20 0.51
▸ ATM Q13315 1/20 0.51
▸ CYP3A4 P08684 5/20 0.50
▸ ALOX15 P16050 4/20 0.50
▸ POLB P06746 1/20 0.50
▸ LMNA P02545 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24928 0.87 ALDH1A1 (0.64) GAATHRBTDP1ALDH1A1TSHR
2-Amino-4-Nitrophenol SCHEMBL22943 0.87 GAA (1.00) GAATHRBTDP1ALDH1A1TSHR
2-Amino-4-Nitrophenol SCHEMBL31297314 0.87 GAA (1.00) GAATHRBTDP1ALDH1A1TSHR
SCHEMBL29622134 0.87 ALDH1A1 (0.64) GAATHRBTDP1ALDH1A1TSHR
2-Amino-4-Nitrophenol SCHEMBL23143548 0.85 GAA (0.67) GAATHRBTDP1ALDH1A1TSHR
2-Amino-4-Nitrophenol SCHEMBL11137165 0.85 GAA (0.96) GAATHRBTDP1ALDH1A1TSHR
2-Amino-4-Nitrophenol SCHEMBL19950746 0.85 GAA (0.96) GAATHRBTDP1ALDH1A1TSHR
2-Amino-4-Nitrophenol SCHEMBL19950506 0.85 GAA (0.96) GAATHRBTDP1ALDH1A1TSHR
2-Amino-4-Nitrophenol SCHEMBL19950745 0.85 GAA (0.96) GAATHRBTDP1ALDH1A1TSHR
2-Amino-4-Nitrophenol SCHEMBL6894954 0.85 GAA (0.96) GAATHRBTDP1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130269120-A1 DYE COMPOSITION COMPRISING BENZYL ALCOHOL, A MONOALCOHOL AND A PARTICULAR DIRECT DYE L'OREAL (FR) 2013-10-17 — — US disclosed
WO-2006087195-A2 DYE COMPOSITION COMPRISING AT LEAST ONE METHINE DYE OF PARTICULAR STRUCTURE AND PROCESS FOR IMPLEMENTATION THEREOF L'OREAL (FR) 2006-08-24 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130269120-A1 DYE COMPOSITION COMPRISING BENZYL ALCOHOL, A MONOALCOHOL AND A PARTICULAR DIRECT DYE ADH1C, ADH1A, ADH5 GAA 3240/4885THRB 4834/4885TDP1 4178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.