Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GCK | P35557 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24932393 | 0.84 | L3MBTL1 (0.55) | ALDH1A1RAB9ANPC1TP53L3MBTL1 | |
| SCHEMBL29861014 | 0.80 | RAB9A (0.60) | ALDH1A1RAB9ANPC1TP53L3MBTL1 | |
| SCHEMBL24931553 | 0.80 | RAB9A (0.60) | ALDH1A1RAB9ANPC1TP53L3MBTL1 | |
| SCHEMBL24932334 | 0.77 | MAPT (0.55) | TDP1ALDH1A1RAB9ANPC1TP53 | |
| SCHEMBL3466199 | 0.76 | ALDH1A1 (0.50) | ALDH1A1RAB9ANPC1TP53L3MBTL1 | |
| SCHEMBL29929642 | 0.76 | GCK (0.48) | TDP1ALDH1A1RAB9ANPC1TP53 | |
| SCHEMBL19699480 | 0.74 | FFAR2 (0.62) | ALDH1A1RAB9ANPC1TP53L3MBTL1 | |
| SCHEMBL29563851 | 0.74 | TSHR (0.44) | ALDH1A1RAB9ANPC1TP53L3MBTL1 | |
| SCHEMBL27210883 | 0.74 | TSHR (0.44) | ALDH1A1RAB9ANPC1TP53L3MBTL1 | |
| SCHEMBL24931564 | 0.73 | ALDH1A1 (0.51) | TDP1ALDH1A1RAB9ANPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230027929-A1 | MrgprX2 Antagonists and Uses Thereof | DERMIRA, INC. | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230027929-A1 | MrgprX2 Antagonists and Uses Thereof | MRGPRX2, MRGPRX1, MRGPRX4 | TDP1 4076/4885ALDH1A1 2645/4885RAB9A 1911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.