Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2493369 | 0.98 | KMT2A (0.69) | KMT2ALMNARAB9ASMN1; SMN2CYP2D6 | |
| SCHEMBL5731047 | 0.81 | KMT2A (0.67) | KMT2ALMNARAB9ASMN1; SMN2CYP2D6 | |
| SCHEMBL5731969 | 0.81 | KMT2A (0.67) | KMT2ALMNARAB9ASMN1; SMN2CYP2D6 | |
| SCHEMBL5733176 | 0.81 | KMT2A (0.97) | KMT2ALMNARAB9ASMN1; SMN2CYP2D6 | |
| SCHEMBL5732043 | 0.81 | KMT2A (0.67) | KMT2ALMNARAB9ASMN1; SMN2CYP2D6 | |
| Bromide SCHEMBL3176423 | 0.80 | KMT2A (0.65) | KMT2ALMNARAB9ASMN1; SMN2CYP2D6 | |
| SCHEMBL8152659 | 0.80 | KMT2A (0.57) | KMT2ALMNARAB9ASMN1; SMN2CYP2D6 | |
| Bromide SCHEMBL3173149 | 0.79 | KMT2A (0.56) | KMT2ALMNARAB9ASMN1; SMN2CYP2D6 | |
| SCHEMBL5731245 | 0.77 | KMT2A (0.58) | KMT2ALMNARAB9ASMN1; SMN2CYP2D6 | |
| SCHEMBL3163430 | 0.77 | MAPT (0.65) | KMT2ALMNARAB9ASMN1; SMN2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219898-A1 | COMPOUNDS AND METHODS FOR BLOCKING APOPTOSIS AND INDUCING AUTOPHAGY | HARVARD COLLEGE (US) | 2023-07-13 | — | — | US | disclosed |
| US-20230219898-A1 | COMPOUNDS AND METHODS FOR BLOCKING APOPTOSIS AND INDUCING AUTOPHAGY | HARVARD COLLEGE (US) | 2023-07-13 | — | — | US | disclosed |
| WO-2021257697-A1 | COMPOUNDS AND METHODS FOR BLOCKING APOPTOSIS AND INDUCING AUTOPHAGY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-12-23 | — | — | WO | disclosed |
| EP-2380208-A1 | SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND | E. I. du Pont de Nemours and Company (US) | 2011-10-26 | — | — | EP | disclosed |
| WO-2010085664-A1 | SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-07-29 | — | — | WO | disclosed |
| EP-1651613-A1 | 4,5-DIHYDRO-IMIDAZOLE AS P2X7 ION CHANNEL BLOCKERS | Aventis Pharmaceuticals, Inc. (US) | 2006-05-03 | — | — | EP | disclosed |
| WO-2005014555-A1 | 4,5-DIHYDRO-IMIDAZOLE AS P2X7 ION CHANNEL BLOCKERS | AVENTIS PHARMACEUTICALS INC. (US) | 2005-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219898-A1 | COMPOUNDS AND METHODS FOR BLOCKING APOPTOSIS AND INDUCING AUTOPHAGY | BECN1, SQSTM1, ATG7 | KMT2A 3871/4885LMNA 1096/4885RAB9A 326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.