Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.30 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.30 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CCND1 | P24385 | 1/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24935230 | 0.82 | MRGPRX4 (0.46) | MRGPRX4 | |
| SCHEMBL24934753 | 0.82 | KDM4E (0.33) | ALDH1A1MAPK1KDM4EHPGDHSD17B10 | |
| SCHEMBL24935694 | 0.77 | L3MBTL1 (0.42) | HPGDCYP3A4MAPT | |
| SCHEMBL25063758 | 0.74 | EIF4A3 (0.33) | CYP3A4MRGPRX4 | |
| SCHEMBL22877078 | 0.70 | THRA (0.42) | MAPK1MAPT | |
| SCHEMBL24935659 | 0.69 | MRGPRX4 (0.44) | ALDH1A1MAPTADORA3MRGPRX4 | |
| SCHEMBL24935232 | 0.69 | PPARD (0.38) | ALDH1A1KDM4EHPGDMAPTRAB9A | |
| SCHEMBL25063930 | 0.67 | EIF4A3 (0.38) | ALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL19019341 | 0.66 | KDM4E (0.34) | ALDH1A1KDM4EMAPT | |
| SCHEMBL24934755 | 0.66 | MRGPRX4 (0.41) | ALDH1A1HPGDCYP3A4MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119546-A1 | BIFUNCTIONAL COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | Suzhou Kintor Pharmaceuticals, Inc. (CN) | 2023-01-18 | — | — | EP | disclosed |