SCHEMBL24935705

SCHEMBL24935705

CC(C)C(=O)C1CCN(C2CCN(C(=O)c3ccc(C(C)C)cc3)CC2)CC1

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL3 Q96JM7 15/20 0.56
L3MBTL1 Q9Y468 13/20 0.56
MBTD1 Q05BQ5 5/20 0.56
TP53BP1 Q12888 2/20 0.56
L3MBTL4 Q8NA19 2/20 0.56
MEN1 O00255 1/20 0.55
ALDH1A1 P00352 1/20 0.55
LMNA P02545 1/20 0.55
KMT2A Q03164 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
MAPT P10636 1/20 0.54
MGLL Q99685 3/20 0.52
FAAH O00519 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13354592 0.85 L3MBTL3 (0.77) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL19226528 0.83 ALDH1A1 (0.69) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL14924017 0.81 L3MBTL3 (0.73) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL3919816 0.80 ALDH1A1 (0.70) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL20116334 0.80 MAPT (0.70) MEN1ALDH1A1LMNAKMT2ASMN1; SMN2
SCHEMBL13295895 0.80 MGLL (0.59) L3MBTL3MEN1KMT2AMAPTMGLL
SCHEMBL20013935 0.80 ALDH1A1 (0.69) L3MBTL3MEN1ALDH1A1LMNAKMT2A
SCHEMBL13295892 0.78 ACHE (0.69) L3MBTL3L3MBTL1MEN1ALDH1A1KMT2A
SCHEMBL14923995 0.77 KMT2A (0.69) L3MBTL3L3MBTL1MEN1ALDH1A1LMNA
SCHEMBL16845111 0.77 ADRA1A (0.61) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4119546-A1 BIFUNCTIONAL COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF Suzhou Kintor Pharmaceuticals, Inc. (CN) 2023-01-18 EP disclosed