Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.39 |
| ▸ | WDR5 | P61964 | 3/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.31 |
| ▸ | CPB1 | P15086 | 1/20 | 0.30 |
| ▸ | PDE1A | P54750 | 1/20 | 0.30 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.30 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24936213 | 0.93 | PHF8 (0.42) | KDM4CCPB2WDR5PHF8CYP2B6 | |
| SCHEMBL19859618 | 0.77 | CHRNB2 (0.39) | — | |
| SCHEMBL22833771 | 0.74 | KDM4C (0.42) | KDM4CCPB2WDR5PHF8CYP2B6 | |
| Hydrochloric Acid SCHEMBL23389331 | 0.72 | CPB2 (0.43) | KDM4CCPB2WDR5PHF8CYP2B6 | |
| SCHEMBL10064777 | 0.72 | CYP2E1 (0.40) | CPB2CYP2B6 | |
| SCHEMBL19700911 | 0.72 | PI4KA (0.33) | — | |
| SCHEMBL18250305 | 0.70 | CDK5 (0.37) | CPB2WDR5KDM2B | |
| SCHEMBL24936215 | 0.70 | CNR2 (0.34) | CNR2CYP11B2ATAD2PDE1APDE1B | |
| SCHEMBL26151609 | 0.70 | RAB9A (0.47) | — | |
| SCHEMBL10223624 | 0.70 | KDM2B (0.44) | KDM4CKDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230022304-A1 | WDR5-MYC INHIBITORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230022304-A1 | WDR5-MYC INHIBITORS | MYC, WDR5, MYCBP | KDM4C 1517/4885CPB2 4752/4885WDR5 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.