Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 8/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | BCR | P11274 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | BAX | Q07812 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | SCN4A | P35499 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3481948 | 0.80 | SYK (0.37) | TSHRABL1ABCB1BCRHPGD | |
| SCHEMBL15067819 | 0.76 | SLC6A2 (0.50) | GSTP1PTGS2HDAC8 | |
| SCHEMBL6683476 | 0.75 | ALDH1A1 (0.38) | TSHRABL1ABCB1BCR | |
| SCHEMBL15847174 | 0.74 | ALDH1A1 (0.47) | LTA4HTSHRHPGD | |
| SCHEMBL15847175 | 0.74 | LTA4H (0.58) | GSTP1LTA4HTSHRNR1H2BAX | |
| SCHEMBL20483376 | 0.73 | PTGS2 (0.55) | GSTP1LTA4HPTGS2NCOA1NCOA3 | |
| Hydrogen Sulfide SCHEMBL27719824 | 0.73 | GSTP1 (0.63) | GSTP1LTA4HTSHRPTGS2ABL1 | |
| SCHEMBL11751812 | 0.72 | GSTP1 (0.61) | GSTP1LTA4HTSHRPTGS2ABL1 | |
| SCHEMBL10711068 | 0.70 | NCOA1 (0.69) | GSTP1LTA4HTSHRPTGS2NR1H2 | |
| SCHEMBL6406035 | 0.70 | LTA4H (0.75) | GSTP1LTA4HTSHRNR1H2BAX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637627-B2 | Phenoxyphenyl polysiloxane composition and method for making and using same | ROHM AND HAAS COMPANY (US) | 2014-01-28 | — | — | US | disclosed |
| US-8029904-B2 | Aryl (thio)ether aryl polysiloxane composition and methods for making and using same | ROHM AND HAAS COMPANY (US) | 2011-10-04 | — | — | US | disclosed |
| EP-1927636-B1 | Aryl(thio)ether aryl polysiloxane composition and methods for making and using same | ROHM & HAAS (US) | 2010-02-10 | — | — | EP | disclosed |
| US-20090146324-A1 | Phenoxyphenyl polysiloxane composition and method for making and using same | ROHM AND HAAS COMPANY (US) | 2009-06-11 | — | — | US | disclosed |
| US-20080160323-A1 | Hydrosilation catalysts; for encapsulating semiconductors | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2008-07-03 | — | — | US | disclosed |
| EP-1927636-A1 | Aryl(thio)ether aryl polysiloxane composition and methods for making and using same | Rohm and Haas Company (US) | 2008-06-04 | — | — | EP | disclosed |