SCHEMBL6683476

SCHEMBL6683476

C=Cc1ccc(-c2ccccc2[SiH](OC)OC)cc1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
TSHR P16473 1/20 0.38
ABL1 P00519 1/20 0.32
ABCB1 P08183 1/20 0.32
BCR P11274 1/20 0.32
DRD1 P21728 3/20 0.31
TRPA1 O75762 1/20 0.31
DRD2 P14416 1/20 0.30
DRD4 P21917 1/20 0.30
DRD5 P21918 1/20 0.30
DRD3 P35462 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3481948 0.79 SYK (0.37) ALDH1A1TSHRABL1ABCB1BCR
SCHEMBL14247803 0.77 ALDH1A1 (0.41) ALDH1A1TSHRABL1DRD1
SCHEMBL2493745 0.75 GSTP1 (0.49) TSHRABL1ABCB1BCR
SCHEMBL896204 0.74 XDH (0.47) ALDH1A1TSHRDRD1TRPA1DRD2
SCHEMBL8759106 0.72 ALDH1A1 (0.59) ALDH1A1TSHRDRD1
SCHEMBL28116543 0.72 ALDH1A1 (0.48) ALDH1A1TSHRTRPA1
SCHEMBL4456341 0.71 CA12 (0.47) ALDH1A1TSHRDRD1TRPA1
SCHEMBL143427 0.71 ALDH1A1 (0.40) ALDH1A1TSHR
SCHEMBL8103451 0.70 ALDH1A1 (0.50) ALDH1A1TSHRTRPA1
SCHEMBL28928500 0.70 ALDH1A1 (0.56) ALDH1A1TSHRDRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823450-B1 COMPOSITE AND MOLDINGS PRODUCED THEREFROM MITSUBISHI RAYON CO (JP) 2004-11-24 EP disclosed
EP-0696621-B1 COATING COMPOSITION AND SURFACE-COATED MOLDING PRODUCED THEREWITH MITSUBISHI RAYON CO (JP) 2000-10-11 EP disclosed
EP-0823450-A1 COMPOSITE AND MOLDINGS PRODUCED THEREFROM MITSUBISHI RAYON CO., LTD. (JP) 1998-02-11 EP disclosed
US-5695851-A CROSSLINKABLE, POLYMERIZABLE COMPOSITION CONTAINING (METH)ACRYLOYLOXY GROUPS, SILICA WHOSE SURFACE HAS BEEN MODIFIED WITH AN ORGANOSILANE-CONTAINING COMPOUND, AND A HIGH ENERGY RADIATION POLYMERIZATION INITIATOR MITSUBISHI RAYON CO., LTD. (JP) 1997-12-09 US disclosed
EP-0696621-A1 COATING COMPOSITION AND SURFACE-COATED MOLDING PRODUCED THEREWITH MITSUBISHI RAYON CO., LTD. (JP) 1996-02-14 EP disclosed