Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11553231 | 0.75 | ALDH1A1 (0.53) | PTGS2ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL21740733 | 0.73 | PTGS2 (0.53) | PTGS2HTR2AHTR2CHTR2B | |
| SCHEMBL8230395 | 0.73 | PTGS2 (0.68) | PTGS2HTR2AHTR2CHTR2BCYP3A4 | |
| SCHEMBL2307800 | 0.72 | PTGS2 (0.55) | PTGS2ALDH1A1GAAKDM4EHTR2A | |
| SCHEMBL6845422 | 0.71 | PTGS2 (0.59) | PTGS2KDM4EHTR2AHTR2CHTR2B | |
| SCHEMBL20179601 | 0.71 | TUBB4A (0.58) | PTGS2KDM4EKMT2ACYP3A4SMN1; SMN2 | |
| SCHEMBL4240508 | 0.70 | PTGS2 (0.53) | PTGS2ALDH1A1GAAKDM4EHTR2A | |
| SCHEMBL21102118 | 0.70 | CA2 (0.59) | ALDH1A1GAAKDM4EKMT2AMAPK1 | |
| SCHEMBL4683243 | 0.70 | KDM4E (0.55) | PTGS2ALDH1A1GAAKDM4EHTR2A | |
| SCHEMBL21101917 | 0.70 | KDM4E (0.55) | ALDH1A1GAAKDM4EKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119552-A1 | REGULATING CHIMERIC ANTIGEN RECEPTORS | Dana-Farber Cancer Institute, Inc. (US) | 2023-01-18 | — | — | EP | disclosed |