SCHEMBL24939705

SCHEMBL24939705

CC1=CC(=O)N(Cc2ccc(C(=O)O)cc2)C1=O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.61
PTGS2 P35354 1/20 0.61
ENPP2 Q13822 1/20 0.55
KMT2A Q03164 5/20 0.53
MEN1 O00255 4/20 0.53
POLB P06746 4/20 0.53
ALDH1A1 P00352 3/20 0.53
MAPT P10636 3/20 0.53
GAA P10253 2/20 0.53
THRB P10828 2/20 0.53
RECQL P46063 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
KDM4E B2RXH2 1/20 0.53
USP2 O75604 1/20 0.53
NR4A1 P22736 1/20 0.53
APEX1 P27695 1/20 0.53
APOBEC3A P31941 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
HIF1A Q16665 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1133156 0.87 MGLL (0.50) PTGS1PTGS2CA1CA2CA9
SCHEMBL8931456 0.84 PTGS1 (0.45) PTGS1PTGS2ENPP2KMT2AMEN1
SCHEMBL907301 0.82 RGS4 (0.64) KMT2AMEN1ALDH1A1MAPTHPGD
SCHEMBL24939709 0.80 PTGS1 (0.64) PTGS1PTGS2ENPP2KMT2AMEN1
Hydrochloric Acid SCHEMBL7466609 0.79 PTGS1 (0.62) PTGS1PTGS2ENPP2KMT2AMEN1
SCHEMBL3034487 0.76 PTGS1 (1.00) PTGS1PTGS2ENPP2KMT2AMEN1
SCHEMBL2643077 0.76 GSK3A (0.63) KMT2AMEN1ALDH1A1MAPTGAA
SCHEMBL31753078 0.76 KMT2A (0.74) PTGS1PTGS2ENPP2KMT2AMEN1
SCHEMBL916927 0.76 KMT2A (0.74) PTGS1PTGS2ENPP2KMT2AMEN1
SCHEMBL4239479 0.73 ENPP2 (0.88) PTGS1PTGS2ENPP2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230022129-A1 RESIST MATERIAL AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230022129-A1 RESIST MATERIAL AND PATTERNING PROCESS GFER, LBR, PCNA PTGS1 3908/4885PTGS2 3014/4885ENPP2 4692/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.