Nedocromil

Nedocromil

SCHEMBL24943

CCCc1c2oc(C(=O)O)cc(=O)c2cc2c(=O)cc(C(=O)O)n(CC)c12.[NaH]

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PDE5A O76074 4/20 0.46
ABCB11 O95342 1/20 0.43
CYSLTR2 Q9NS75 2/20 0.41
CYSLTR1 Q9Y271 2/20 0.41
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
TBXAS1 P24557 1/20 0.41
KMT2A Q03164 1/20 0.41
GPR35 Q9HC97 12/20 0.38
KDM4E B2RXH2 2/20 0.35
POLB P06746 1/20 0.35
PKM P14618 1/20 0.35
USP2 O75604 1/20 0.33
CSNK2A2 P19784 1/20 0.33
PTGS1 P23219 1/20 0.33
CSNK2B P67870 1/20 0.33
CSNK2A1 P68400 1/20 0.33
CSNK2A3 Q8NEV1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nedocromil SCHEMBL20481863 1.00 PDE5A (0.46) PDE5AABCB11CYSLTR2CYSLTR1MEN1
Nedocromil SCHEMBL316743 1.00 PDE5A (0.46) PDE5AABCB11CYSLTR2CYSLTR1MEN1
Nedocromil SCHEMBL4611 0.99 PDE5A (0.47) PDE5AABCB11CYSLTR2CYSLTR1MEN1
Nedocromil SCHEMBL29406688 0.99 PDE5A (0.47) PDE5AABCB11CYSLTR2CYSLTR1MEN1
Nedocromil SCHEMBL667050 0.98 PDE5A (0.46) PDE5AABCB11CYSLTR2CYSLTR1MEN1
Nedocromil SCHEMBL2879046 0.98 PDE5A (0.46) PDE5AABCB11CYSLTR2CYSLTR1MEN1
Nedocromil SCHEMBL28341341 0.98 PDE5A (0.46) PDE5AABCB11CYSLTR2CYSLTR1MEN1
Nedocromil SCHEMBL17274068 0.96 PDE5A (0.44) PDE5AABCB11CYSLTR2CYSLTR1MEN1
Nedocromil SCHEMBL22028284 0.94 PDE5A (0.44) PDE5AABCB11CYSLTR2CYSLTR1MEN1
Nedocromil SCHEMBL17473185 0.93 PDE5A (0.43) PDE5AABCB11CYSLTR2CYSLTR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8568 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4058037-B1 FIBROBLAST-BASED THERAPY FOR TREATMENT AND PREVENTION OF STROKE SPINALCYTE LLC (US) 2026-01-28 EP claimed
EP-4590283-A1 MUCOADHESIVE DRUG DELIVERY SYSTEMS AND METHODS OF USE Madd Ophthalmics Ltd. (CA) 2025-07-30 EP claimed
CN-119176762-A Preparation method of nedocromil sodium key intermediate 3-acetamido-4, 6-diacetylphenol 南京康立瑞生物科技有限公司 2024-12-24 CN claimed
CN-119080626-A Preparation method for preparing nedocromil sodium key intermediate by using continuous flow technology 南京康立瑞生物科技有限公司 2024-12-06 CN claimed
CN-118662629-A Methods of treating inflammatory conditions 瑞泽恩制药公司 2024-09-20 CN claimed
US-20240199751-A1 METHODS FOR TREATING OR PREVENTING ASTHMA BY ADMINISTERING AN IL-4R ANTAGONIST SANOFI BIOTECHNOLOGY (FR) 2024-06-20 US claimed
CN-110167963-B Methods of treating inflammatory conditions 瑞泽恩制药公司 2024-06-14 CN claimed
US-20240123168-A1 PRODUCT DELIVERY DEVICES AND METHODS MUSTAPHA JIHAD A (US) 2024-04-18 US claimed
WO-2024059952-A1 MUCOADHESIVE DRUG DELIVERY SYSTEMS AND METHODS OF USE MADD OPHTHALMICS LTD. (CA) 2024-03-28 WO claimed
EP-4324479-A2 METHODS FOR TREATING OR PREVENTING ASTHMA BY ADMINISTERING AN IL-4R ANTAGONIST Sanofi Biotechnology (FR) 2024-02-21 EP claimed
US-4868192-A SKIN DISORDERS FISONS PLC (GB) 1989-09-19 US claimed
US-4866072-A Method of treating cystic fibrosis FISONS PLC (GB) 1989-09-12 US claimed
EP-0318211-A1 Nedocromil sodium compositions and methods for their preparation FISONS plc (GB) 1989-05-31 EP claimed
EP-0294940-A1 Pharmaceutical compositions FISONS plc (GB) 1988-12-14 EP claimed
EP-0294914-A2 Nedocromil for the treatment of dermatological disorders FISONS plc (GB) 1988-12-14 EP claimed
EP-0287193-A2 Use of nedocromil sodium in the treatment of cystic fibrosis FISONS plc (GB) 1988-10-19 EP claimed
EP-0279121-A2 Pharmaceutical compositions comprising an aqueous solution of a pyranoquinoline derivative FISONS plc (GB) 1988-08-24 EP claimed
US-4760072-A Crystalline and contains bound water; treats reversible obstructive condition of airways in a mammal FISONS, PLC (GB) 1988-07-26 US claimed
EP-0241134-A1 Pharmaceutical mixture comprising nedocromil or a salt thereof in combination with a bronchodilator FISONS plc (GB) 1987-10-14 EP claimed
EP-0162556-A1 Novels forms and formulations of nedocromil sodium FISONS plc (GB) 1985-11-27 EP claimed