Nedocromil

Nedocromil

SCHEMBL2879046

CCCc1c2oc(C(=O)O)cc(=O)c2cc2c(=O)cc(C(=O)O)n(CC)c12.[MgH2]

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PDE5A O76074 4/20 0.46
ABCB11 O95342 1/20 0.43
CYSLTR2 Q9NS75 2/20 0.41
CYSLTR1 Q9Y271 2/20 0.41
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
TBXAS1 P24557 1/20 0.41
KMT2A Q03164 1/20 0.41
GPR35 Q9HC97 12/20 0.38
KDM4E B2RXH2 2/20 0.35
POLB P06746 1/20 0.35
PKM P14618 1/20 0.35
USP2 O75604 1/20 0.33
CSNK2A2 P19784 1/20 0.33
PTGS1 P23219 1/20 0.33
CSNK2B P67870 1/20 0.33
CSNK2A1 P68400 1/20 0.33
CSNK2A3 Q8NEV1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nedocromil SCHEMBL29406688 0.99 PDE5A (0.47) PDE5AABCB11CYSLTR2CYSLTR1MEN1
Nedocromil SCHEMBL4611 0.99 PDE5A (0.47) PDE5AABCB11CYSLTR2CYSLTR1MEN1
Nedocromil SCHEMBL24943 0.98 PDE5A (0.46) PDE5AABCB11CYSLTR2CYSLTR1MEN1
Nedocromil SCHEMBL20481863 0.98 PDE5A (0.46) PDE5AABCB11CYSLTR2CYSLTR1MEN1
Nedocromil SCHEMBL28341341 0.98 PDE5A (0.46) PDE5AABCB11CYSLTR2CYSLTR1MEN1
Nedocromil SCHEMBL667050 0.98 PDE5A (0.46) PDE5AABCB11CYSLTR2CYSLTR1MEN1
Nedocromil SCHEMBL316743 0.98 PDE5A (0.46) PDE5AABCB11CYSLTR2CYSLTR1MEN1
Nedocromil SCHEMBL22028284 0.94 PDE5A (0.44) PDE5AABCB11CYSLTR2CYSLTR1MEN1
Nedocromil SCHEMBL17274068 0.94 PDE5A (0.44) PDE5AABCB11CYSLTR2CYSLTR1MEN1
Nedocromil SCHEMBL17473185 0.93 PDE5A (0.43) PDE5AABCB11CYSLTR2CYSLTR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7663107-B2 Method and apparatus for quantitative analysis using terahertz radiation TERAVIEW LIMITED (GB) 2010-02-16 US disclosed
US-7244934-B2 Analysis apparatus and method TERAVIEW LIMITED (GB) 2007-07-17 US disclosed
US-20060237650-A1 Method and apparatus for quantitative analysis using terahertz radiation TERAVIEW LIMITED (GB) 2006-10-26 US disclosed
EP-1634064-A1 METHOD AND APPARATUS FOR QUANTITATIVE ANALYSIS USING TERAHERTZ RADIATION TeraView Limited (GB) 2006-03-15 EP disclosed
US-20050156120-A1 Analysis apparatus and method ETV CAPITAL S.A. (LU) 2005-07-21 US disclosed
WO-2004106905-A1 METHOD AND APPARATUS FOR QUANTITATIVE ANALYSIS USING TERAHERTZ RADIATION TERAVIEW LIMITED (GB) 2004-12-09 WO disclosed
EP-1474675-A2 AN ANALYSIS APPARATUS AND METHOD Teraview Limited (GB) 2004-11-10 EP disclosed
WO-2003069318-A2 AN ANALYSIS APPARATUS AND METHOD TERAVIEW LIMITED (GB) 2003-08-21 WO disclosed