Nedocromil

Nedocromil

SCHEMBL4611

CCCc1c2oc(C(=O)O)cc(=O)c2cc2c(=O)cc(C(=O)O)n(CC)c12

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PDE5A O76074 4/20 0.47
ABCB11 O95342 1/20 0.43
CYSLTR2 Q9NS75 2/20 0.41
CYSLTR1 Q9Y271 2/20 0.41
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
TBXAS1 P24557 1/20 0.41
KMT2A Q03164 1/20 0.41
GPR35 Q9HC97 12/20 0.38
KDM4E B2RXH2 2/20 0.36
POLB P06746 1/20 0.36
PKM P14618 1/20 0.36
USP2 O75604 1/20 0.34
CSNK2A2 P19784 1/20 0.34
PTGS1 P23219 1/20 0.34
CSNK2B P67870 1/20 0.34
CSNK2A1 P68400 1/20 0.34
CSNK2A3 Q8NEV1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nedocromil SCHEMBL29406688 1.00 PDE5A (0.47) PDE5AABCB11CYSLTR2CYSLTR1MEN1
Nedocromil SCHEMBL2879046 0.99 PDE5A (0.46) PDE5AABCB11CYSLTR2CYSLTR1MEN1
Nedocromil SCHEMBL20481863 0.99 PDE5A (0.46) PDE5AABCB11CYSLTR2CYSLTR1MEN1
Nedocromil SCHEMBL28341341 0.99 PDE5A (0.46) PDE5AABCB11CYSLTR2CYSLTR1MEN1
Nedocromil SCHEMBL24943 0.99 PDE5A (0.46) PDE5AABCB11CYSLTR2CYSLTR1MEN1
Nedocromil SCHEMBL667050 0.99 PDE5A (0.46) PDE5AABCB11CYSLTR2CYSLTR1MEN1
Nedocromil SCHEMBL316743 0.99 PDE5A (0.46) PDE5AABCB11CYSLTR2CYSLTR1MEN1
Nedocromil SCHEMBL22028284 0.95 PDE5A (0.44) PDE5AABCB11CYSLTR2CYSLTR1MEN1
Nedocromil SCHEMBL17274068 0.95 PDE5A (0.44) PDE5AABCB11CYSLTR2CYSLTR1MEN1
Nedocromil SCHEMBL5968262 0.94 PDE5A (0.43) PDE5AABCB11CYSLTR2CYSLTR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 15045 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6423298-B1 None US claimed
EP-4747263-A1 LIPID NANOPARTICLES AND USES THEREOF University of Connecticut (US) 2026-05-27 EP claimed
US-20260137558-A1 OPHTHALMIC DEVICE Able Tx Ltd. (IL) 2026-05-21 US claimed
US-12616803-B2 Apparatus for dispensing inhalant medicament METOPI PHARMACEUTICALS, INC. (US) 2026-05-05 US claimed
EP-4724079-A2 METHODS AND COMPOSITIONS FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION Stealth BioTherapeutics Inc. (US) 2026-04-15 EP claimed
EP-4434588-B1 AEROSOL DELIVERY DEVICE PARI PHARMA GMBH (DE) 2026-04-08 EP claimed
US-20260076872-A1 POLYMER VIALS WITH SUBSTANTIALLY FLAT BOTTOMS AND INJECTION STRETCH BLOW MOLDING METHODS FOR MAKING THE SAME SIO2 MEDICAL PRODUCTS LLC (US) 2026-03-19 US claimed
US-12569451-B2 Bio-inspired tissue-adhesive hydrogel patch and uses thereof Cellartgen Inc. (KR) 2026-03-10 US claimed
US-20260048096-A1 METHODS AND COMPOSITIONS FOR PRESERVING THE RETINAL OUTER NUCLEAR LAYER (ONL), PHOTORECEPTORS, AND RETINAL THICKNESS STEALTH BIOTHERAPEUTICS INC. (US) 2026-02-19 US claimed
US-20260042870-A1 BINDER COMPOSITIONS AND USES THEREOF KNAUF INSULATION SPRL (BE) 2026-02-12 US claimed
US-4866072-A Method of treating cystic fibrosis FISONS PLC (GB) 1989-09-12 US claimed
EP-0318211-A1 Nedocromil sodium compositions and methods for their preparation FISONS plc (GB) 1989-05-31 EP claimed
EP-0294940-A1 Pharmaceutical compositions FISONS plc (GB) 1988-12-14 EP claimed
EP-0294914-A2 Nedocromil for the treatment of dermatological disorders FISONS plc (GB) 1988-12-14 EP claimed
EP-0287193-A2 Use of nedocromil sodium in the treatment of cystic fibrosis FISONS plc (GB) 1988-10-19 EP claimed
EP-0285246-A1 Calcium-4,6-dioxo-4h-pyrano[3,2-g]-quinoline-2,8-dicarboxylate derivative, methods for its preparation and compositions containing it FISONS plc (GB) 1988-10-05 EP claimed
EP-0279121-A2 Pharmaceutical compositions comprising an aqueous solution of a pyranoquinoline derivative FISONS plc (GB) 1988-08-24 EP claimed
EP-0272057-A2 Pharmaceutical compositions containing pyranoquinolines FISONS plc (GB) 1988-06-22 EP claimed
EP-0241134-A1 Pharmaceutical mixture comprising nedocromil or a salt thereof in combination with a bronchodilator FISONS plc (GB) 1987-10-14 EP claimed
US-4474787-A 7,6 Dioxo-4H,6H-pyrano[3,2-g]quinoline dicarboxylic acids and anti-allergic use thereof FISONS LIMITED (GB) 1984-10-02 US claimed