Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 4/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 12/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nedocromil SCHEMBL20481863 | 1.00 | PDE5A (0.46) | PDE5AABCB11CYSLTR2CYSLTR1MEN1 | |
| Nedocromil SCHEMBL24943 | 1.00 | PDE5A (0.46) | PDE5AABCB11CYSLTR2CYSLTR1MEN1 | |
| Nedocromil SCHEMBL4611 | 0.99 | PDE5A (0.47) | PDE5AABCB11CYSLTR2CYSLTR1MEN1 | |
| Nedocromil SCHEMBL29406688 | 0.99 | PDE5A (0.47) | PDE5AABCB11CYSLTR2CYSLTR1MEN1 | |
| Nedocromil SCHEMBL667050 | 0.98 | PDE5A (0.46) | PDE5AABCB11CYSLTR2CYSLTR1MEN1 | |
| Nedocromil SCHEMBL2879046 | 0.98 | PDE5A (0.46) | PDE5AABCB11CYSLTR2CYSLTR1MEN1 | |
| Nedocromil SCHEMBL28341341 | 0.98 | PDE5A (0.46) | PDE5AABCB11CYSLTR2CYSLTR1MEN1 | |
| Nedocromil SCHEMBL17274068 | 0.96 | PDE5A (0.44) | PDE5AABCB11CYSLTR2CYSLTR1MEN1 | |
| Nedocromil SCHEMBL22028284 | 0.94 | PDE5A (0.44) | PDE5AABCB11CYSLTR2CYSLTR1MEN1 | |
| Nedocromil SCHEMBL17473185 | 0.93 | PDE5A (0.43) | PDE5AABCB11CYSLTR2CYSLTR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8034839-B2 | Method of treating ocular allergy | ALCON RESEARCH, LTD. (US) | 2011-10-11 | — | — | US | claimed |
| WO-2011096941-A1 | METHOD OF TREATING OCULAR ALLERGY | ALCON RESEARCH, LTD. (US) | 2011-08-11 | — | — | WO | claimed |
| US-20100160298-A1 | METHOD OF TREATING OCULAR ALLERGY | ALCON RESEARCH, LTD. (US) | 2010-06-24 | — | — | US | claimed |
| US-7687539-B1 | Method of treating ocular allergy | ALCON RESEARCH, LTD. (US) | 2010-03-30 | — | — | US | claimed |
| EP-1993741-B1 | INLINE APPLICATION OF COATINGS | COOK MEDICAL TECHNOLOGIES LLC (US) | 2014-03-19 | — | — | EP | disclosed |
| US-8567410-B2 | Magnet-field controlled active substance transfer for aerosol therapy | ETHRIS GMBH (DE) | 2013-10-29 | — | — | US | disclosed |
| US-8523937-B2 | Controlled drug delivery using a zein layer modified with levulinic acid | COOK MEDICAL TECHNOLOGIES LLC (US) | 2013-09-03 | — | — | US | disclosed |
| US-8303648-B2 | Artificial venous valve containing therapeutic agent | COOK MEDICAL TECHNOLOGIES LLC (US) | 2012-11-06 | — | — | US | disclosed |
| US-8092819-B2 | Implantable medical device coated with a bioactive agent | Cook Medical Technologies LLC. (US) | 2012-01-10 | — | — | US | disclosed |
| US-8024851-B2 | Method of producing a radially expandable prosthesis | COOK MEDICAL TECHNOLOGIES LLC (US) | 2011-09-27 | — | — | US | disclosed |
| US-7914841-B2 | Inline application of coatings | COOK MEDICAL TECHNOLOGIES LLC (US) | 2011-03-29 | — | — | US | disclosed |
| EP-1981560-B1 | ZEIN COATED MEDICAL DEVICE | MED INST INC (US) | 2010-09-08 | — | — | EP | disclosed |
| US-20070265699-A1 | Artificial venous valve containing therapeutic agent | MED INSTITUTE, INC. (US) | 2007-11-15 | — | — | US | disclosed |
| US-20070207184-A1 | Implantable medical device coated with a bioactive agent | MED INSTITUTE, INC (US) | 2007-09-06 | — | — | US | disclosed |
| US-20070207183-A1 | Zein coated medical device | MED INSTITUTE, INC. (US) | 2007-09-06 | — | — | US | disclosed |
| US-20070196481-A1 | Sustained-release tablet composition | PHARMACIA CORPORATION | 2007-08-23 | — | — | US | disclosed |
| US-20070196423-A1 | Implantable medical device coatings with biodegradable elastomer and releasable therapeutic agent | MED INSTITUTE, INC. (US) | 2007-08-23 | — | — | US | disclosed |
| WO-2007089592-A2 | IMPLANTABLE MEDICAL DEVICE COATED WITH BIOACTIVE AGENT | MED INSTITUTE, INC. (US) | 2007-08-09 | — | — | WO | disclosed |
| US-20070182055-A1 | Inline application of coatings | COOK INCORPORATED (US) | 2007-08-09 | — | — | US | disclosed |
| US-20070043423-A1 | Intraluminal device with a hollow structure | MED INSTITUTE INC. (US) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070196481-A1 | Sustained-release tablet composition | SI, ABCB11, SLC2A9 | PDE5A 1643/4885ABCB11 2/4885CYSLTR2 3526/4885 |
| US-20100160298-A1 | METHOD OF TREATING OCULAR ALLERGY | HRH2, HRH1, HRH4 | PDE5A 365/4885ABCB11 2647/4885CYSLTR2 17/4885 |
| US-20070207183-A1 | Zein coated medical device | PCSK9, ZYX, ZFX | PDE5A 3281/4885ABCB11 89/4885CYSLTR2 1494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.