Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 4/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 12/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nedocromil SCHEMBL29406688 | 0.99 | PDE5A (0.47) | PDE5AABCB11CYSLTR2CYSLTR1MEN1 | |
| Nedocromil SCHEMBL4611 | 0.99 | PDE5A (0.47) | PDE5AABCB11CYSLTR2CYSLTR1MEN1 | |
| Nedocromil SCHEMBL2879046 | 0.98 | PDE5A (0.46) | PDE5AABCB11CYSLTR2CYSLTR1MEN1 | |
| Nedocromil SCHEMBL20481863 | 0.98 | PDE5A (0.46) | PDE5AABCB11CYSLTR2CYSLTR1MEN1 | |
| Nedocromil SCHEMBL28341341 | 0.98 | PDE5A (0.46) | PDE5AABCB11CYSLTR2CYSLTR1MEN1 | |
| Nedocromil SCHEMBL24943 | 0.98 | PDE5A (0.46) | PDE5AABCB11CYSLTR2CYSLTR1MEN1 | |
| Nedocromil SCHEMBL316743 | 0.98 | PDE5A (0.46) | PDE5AABCB11CYSLTR2CYSLTR1MEN1 | |
| Nedocromil SCHEMBL22028284 | 0.94 | PDE5A (0.44) | PDE5AABCB11CYSLTR2CYSLTR1MEN1 | |
| Nedocromil SCHEMBL17274068 | 0.94 | PDE5A (0.44) | PDE5AABCB11CYSLTR2CYSLTR1MEN1 | |
| Nedocromil SCHEMBL17473185 | 0.93 | PDE5A (0.43) | PDE5AABCB11CYSLTR2CYSLTR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0285246-B1 | Calcium-4,6-dioxo-4h-pyrano[3,2-g]-quinoline-2,8-dicarboxylate derivative, methods for its preparation and compositions containing it | FISONS plc (GB) | 1992-01-02 | — | — | EP | claimed |
| EP-0361659-B1 | PHARMACEUTICAL COMPOSITION | FISONS plc (GB) | 1991-12-18 | — | — | EP | claimed |
| EP-0361659-A2 | Pharmaceutical composition | FISONS plc (GB) | 1990-04-04 | — | — | EP | claimed |
| WO-1990002128-A1 | NEDOCROMIL CALCIUM | FISONS PLC (GB) | 1990-03-08 | — | — | WO | claimed |
| US-4849427-A | Nedocromil calcium and use thereof in treatment of reversible obstructive airways disease | FISONS PLC (GB) | 1989-07-18 | — | — | US | claimed |
| EP-0285246-A1 | Calcium-4,6-dioxo-4h-pyrano[3,2-g]-quinoline-2,8-dicarboxylate derivative, methods for its preparation and compositions containing it | FISONS plc (GB) | 1988-10-05 | — | — | EP | claimed |
| JP-2142730-A | — | — | None | — | — | JP | disclosed |
| CN-103271083-B | Multi-functional ionic liquid compositions | 阿拉巴马大学 | 2017-08-11 | — | — | CN | disclosed |
| US-9278134-B2 | Dual functioning ionic liquids and salts thereof | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2016-03-08 | — | — | US | disclosed |
| US-9096743-B2 | Process for forming films, fibers, and beads from chitinous biomass | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2015-08-04 | — | — | US | disclosed |
| US-9023889-B2 | Use of ascorbic acid derivatives for the functionalization of matrices | MERCK PATENT GMBH (DE) | 2015-05-05 | — | — | US | disclosed |
| US-8802596-B2 | Multi-functional ionic liquid compositions for overcoming polymorphism and imparting improved properties for active pharmaceutical, biological, nutritional, and energetic ingredients | BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2014-08-12 | — | — | US | disclosed |
| CN-103271083-A | Multi-functional ionic liquid compositions | UNIV ALABAMA | 2013-09-04 | — | — | CN | disclosed |
| EP-0361659-A2 | Pharmaceutical composition | FISONS plc (GB) | 1990-04-04 | — | — | EP | disclosed |
| EP-0361659-A2 | Pharmaceutical composition | FISONS plc (GB) | 1990-04-04 | — | — | EP | disclosed |
| WO-1990002128-A1 | NEDOCROMIL CALCIUM | FISONS PLC (GB) | 1990-03-08 | — | — | WO | disclosed |
| WO-1990002128-A1 | NEDOCROMIL CALCIUM | FISONS PLC (GB) | 1990-03-08 | — | — | WO | disclosed |
| US-4849427-A | Nedocromil calcium and use thereof in treatment of reversible obstructive airways disease | FISONS PLC (GB) | 1989-07-18 | — | — | US | disclosed |
| US-4849427-A | Nedocromil calcium and use thereof in treatment of reversible obstructive airways disease | FISONS PLC (GB) | 1989-07-18 | — | — | US | disclosed |
| EP-0285246-A1 | Calcium-4,6-dioxo-4h-pyrano[3,2-g]-quinoline-2,8-dicarboxylate derivative, methods for its preparation and compositions containing it | FISONS plc (GB) | 1988-10-05 | — | — | EP | disclosed |