SCHEMBL24944349

SCHEMBL24944349

O=C(OC1(c2ccccc2)CCNCC1)c1ccccc1C(=O)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.42
OPRM1 P35372 2/20 0.40
ALDH1A1 P00352 3/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
USP2 O75604 1/20 0.38
TSHR P16473 1/20 0.38
HSD17B10 Q99714 1/20 0.38
GAA P10253 2/20 0.37
MAPT P10636 1/20 0.37
HTR6 P50406 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
HDAC1 Q13547 1/20 0.36
CDC25B P30305 1/20 0.36
ATM Q13315 1/20 0.36
ABCB1 P08183 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24944039 0.92 CDC25B (0.48) AKR1C3OPRM1ALDH1A1CYP1A2CYP3A4
SCHEMBL24944340 0.91 AKR1C3 (0.49) AKR1C3OPRM1ALDH1A1L3MBTL1CYP1A2
SCHEMBL26413775 0.86 ALDH1A1 (0.46) OPRM1ALDH1A1L3MBTL1USP2TSHR
SCHEMBL24943710 0.86 ALDH1A1 (0.52) AKR1C3OPRM1ALDH1A1CYP1A2TSHR
SCHEMBL24943664 0.86 OPRM1 (0.46) OPRM1ALDH1A1USP2TSHRHSD17B10
SCHEMBL26413623 0.85 OPRM1 (0.41) OPRM1ALDH1A1TSHRHSD17B10MAPT
SCHEMBL24944073 0.85 OPRM1 (0.44) OPRM1ALDH1A1HDAC1ABCB1
SCHEMBL24944311 0.83 HPGD (0.44) OPRM1ALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL24944623 0.83 RXFP1 (0.46) OPRM1ALDH1A1L3MBTL1NPSR1GAA
SCHEMBL24944852 0.82 OPRM1 (0.47) OPRM1CYP3A4CYP2C9CYP2C19NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11644753-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-09 US disclosed
US-11644753-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-09 US disclosed
US-20230131303-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-04-27 US disclosed
US-20230131303-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-04-27 US disclosed
US-20230021453-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11644753-B2 Resist composition and patterning process HNRNPU, NSUN2, HNRNPR AKR1C3 3695/4885OPRM1 775/4885ALDH1A1 4767/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.