SCHEMBL2494532

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2492369	0.88	KIF11 (0.38)	KIF11ESR1ESR2CYP3A4LMNA
	SCHEMBL2490812	0.81	KIF11 (0.39)	KIF11CYP3A4TSHRNPC1MAPT
	SCHEMBL2493499	0.81	SLC6A1 (0.43)	KIF11CYP3A4ALDH1A1NPC1RAB9A
	SCHEMBL2491921	0.80	KIF11 (0.63)	KIF11TSHRALDH1A1ALOX15RECQL
	SCHEMBL2491594	0.78	SLC6A11 (0.45)	CYP3A4LMNAHSD17B10CA2ALDH1A1
	SCHEMBL12199493	0.75	KIF11 (0.52)	KIF11ALDH1A1MEN1RECQLKMT2A
	SCHEMBL2490410	0.72	SLC6A11 (0.50)	KIF11CYP3A4MEN1KMT2A
	SCHEMBL992028	0.72	SLC6A11 (0.50)	KIF11CYP3A4MEN1KMT2A
	SCHEMBL9142722	0.71	KIF11 (0.52)	KIF11ESR1ESR2CYP3A4LMNA
	Bisphenol A SCHEMBL9185720	0.71	ESR1 (0.64)	ESR1ESR2CYP3A4LMNATYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.