SCHEMBL992028

SCHEMBL992028

COc1ccc(C(OCCO)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC6A11 P48066 4/20 0.50
SLC6A1 P30531 2/20 0.50
KIF11 P52732 7/20 0.49
KCNH2 Q12809 1/20 0.46
MEN1 O00255 1/20 0.44
TP53 P04637 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
KMT2A Q03164 1/20 0.44
SLC6A12 P48065 1/20 0.44
SLC6A13 Q9NSD5 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2490410 1.00 SLC6A11 (0.50) SLC6A11SLC6A1KIF11KCNH2MEN1
SCHEMBL12199494 0.94 KIF11 (0.51) SLC6A11SLC6A1KIF11KCNH2MEN1
SCHEMBL2491594 0.93 SLC6A11 (0.45) SLC6A11SLC6A1MEN1TP53CYP1A2
SCHEMBL6040158 0.91 SLC6A11 (0.46) SLC6A11SLC6A1KIF11KCNH2MEN1
SCHEMBL2385290 0.91 SLC6A11 (0.46) SLC6A11SLC6A1KIF11KCNH2MEN1
SCHEMBL2400336 0.91 SLC6A11 (0.46) SLC6A11SLC6A1KIF11KCNH2MEN1
SCHEMBL13575115 0.91 SLC6A11 (0.46) SLC6A11SLC6A1KIF11KCNH2MEN1
SCHEMBL334143 0.90 SLC6A11 (0.48) SLC6A11SLC6A1KIF11KCNH2MEN1
SCHEMBL8860350 0.89 SLC6A11 (0.47) SLC6A11SLC6A1KIF11KCNH2MEN1
SCHEMBL6849984 0.88 SLC6A11 (0.46) SLC6A11SLC6A1KIF11KCNH2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230381323-A1 RELEASABLE CONJUGATES FISH & RICHARDSON PC 2023-11-30 US disclosed
US-11786599-B2 Releasable conjugates QUIAPEG PHARMACEUTICALS AB (SE) 2023-10-17 US disclosed
EP-3130597-B1 OLIGONUCLEOTIDE HAVING A NON-NATURAL NUCLEOTIDE AT THE 5'-TERMINAL KYOWA KIRIN CO LTD (JP) 2021-11-10 EP disclosed
CN-109651396-B Alkylation of alkyl fluoroalkylsulfonates 诺华股份有限公司 2021-09-14 CN disclosed
US-10568822-B2 Melanogenesis inhibitor comprising d-pantothenyl alcohol, and skin-whitening cosmetic containing same melanogenesis inhibitor POLA CHEMICAL INDUSTRIES, INC. (JP) 2020-02-25 US disclosed
EP-3010926-B1 ALKYLATION WITH AN ALKYL FLUOROALKYL SULFONATE NOVARTIS AG (CH) 2019-11-20 EP disclosed
US-10342819-B2 Oligonucleotide having non-natural nucleotide at 5′-terminal thereof KYOWA HAKKO KIRIN CO., LTD. (JP) 2019-07-09 US disclosed
EP-2380567-B1 MELANIN PRODUCTION INHIBITOR POLA CHEM IND INC (JP) 2019-01-16 EP disclosed
EP-2380567-B1 MELANIN PRODUCTION INHIBITOR POLA CHEM IND INC (JP) 2019-01-16 EP disclosed
US-10131908-B2 5′ phosphate mimics ALNYLAM PHARMACEUTICALS, INC. (US) 2018-11-20 US disclosed
EP-0880532-A4 NON-NUCLEOTIDE PHOSPHOROUS ESTER OLIGOMERS PHARMAGENICS INC (US) 1999-06-09 EP disclosed
EP-0880532-A1 NON-NUCLEOTIDE PHOSPHOROUS ESTER OLIGOMERS PHARMAGENICS, INC. (US) 1998-12-02 EP disclosed
EP-0804443-A4 NON-NUCLEOTIDE PHOSPHORUS ESTER OLIGOMERS PHARMAGENICS INC (US) 1998-04-29 EP disclosed
WO-1998013069-A2 FLUORINATED COPOLYMERIC PHARMACEUTICAL ADJUNCTS SUPRATEK PHARMA, INC. (CA) 1998-04-02 WO disclosed
EP-0804443-A1 NON-NUCLEOTIDE PHOSPHORUS ESTER OLIGOMERS PHARMAGENICS, INC. (US) 1997-11-05 EP disclosed
WO-1997028168-A1 NON-NUCLEOTIDE PHOSPHOROUS ESTER OLIGOMERS PHARMAGENICS, INC. (US) 1997-08-07 WO disclosed
WO-1996022297-A9 NON-NUCLEOTIDE PHOSPHORUS ESTER OLIGOMERS 1996-10-03 WO disclosed
WO-1996022297-A1 NON-NUCLEOTIDE PHOSPHORUS ESTER OLIGOMERS PHARMAGENICS, INC. (US) 1996-07-25 WO disclosed
EP-0552185-A1 SYNTHESIS OF OLIGONUCLEOTIDES ZENECA LIMITED (GB) 1993-07-28 EP disclosed
WO-1992006103-A1 SYNTHESIS OF OLIGONUCLEOTIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-04-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10342819-B2 Oligonucleotide having non-natural nucleotide at 5′-terminal thereof RNGTT, UPF1, NSUN3 SLC6A11 4665/4885SLC6A1 4581/4885KIF11 3637/4885
US-10131908-B2 5′ phosphate mimics NSUN2, RNGTT, RNMT SLC6A11 4504/4885SLC6A1 4105/4885KIF11 4094/4885
US-20230381323-A1 RELEASABLE CONJUGATES GUSB, ABCB11, UGT2B7 SLC6A11 1634/4885SLC6A1 1210/4885KIF11 2633/4885
US-10568822-B2 Melanogenesis inhibitor comprising d-pantothenyl alcohol, and skin-whitening cosmetic containing same melanogenesis inhibitor MC1R, TYR, NAMPT SLC6A11 2306/4885SLC6A1 2593/4885KIF11 3669/4885
US-11786599-B2 Releasable conjugates GUSB, ABCB11, UGT2B7 SLC6A11 1634/4885SLC6A1 1210/4885KIF11 2633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.