Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | TLR1 | Q15399 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24951291 | 1.00 | TLR2 (0.39) | TLR2TLR1CYP2C19HIF1AMTNR1A | |
| SCHEMBL28594635 | 0.86 | MTNR1A (0.37) | CYP2C19HIF1AMTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL20151858 | 0.84 | HDAC8 (0.40) | CYP2C19HIF1AMTNR1AMTNR1BL3MBTL1 | |
| Bromide SCHEMBL28950639 | 0.82 | HDAC8 (0.39) | CYP2C19HIF1AMTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL24952122 | 0.80 | LMNA (0.41) | CYP2C19L3MBTL1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL24952207 | 0.80 | LMNA (0.41) | CYP2C19L3MBTL1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL26023523 | 0.79 | L3MBTL1 (0.51) | TLR2TLR1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL24386940 | 0.79 | L3MBTL1 (0.51) | TLR2TLR1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL24207942 | 0.79 | L3MBTL1 (0.51) | TLR2TLR1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3590948 | 0.78 | TDP1 (0.49) | L3MBTL1ALDH1A1KMT2AMEN1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11560395-B2 | Azithromycin derivatives containing a phosphonium ion as anticancer agents | RISING TIDE FOUND (CH) | 2023-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11560395-B2 | Azithromycin derivatives containing a phosphonium ion as anticancer agents | NUP205, PHPT1, PHOSPHO1 | TLR2 4758/4885TLR1 4797/4885CYP2C19 4069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.