Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 2/20 | 0.35 |
| ▸ | ALPI | P09923 | 2/20 | 0.35 |
| ▸ | ALPG | P10696 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28950639 | 0.98 | HDAC8 (0.39) | HDAC8L3MBTL1MTNR1AMTNR1BALPL | |
| SCHEMBL28594635 | 0.90 | MTNR1A (0.37) | L3MBTL1MTNR1AMTNR1BALPLALPI | |
| SCHEMBL24952223 | 0.84 | LTA4H (0.38) | HDAC8L3MBTL1KMT2A | |
| SCHEMBL24951291 | 0.84 | TLR2 (0.39) | L3MBTL1MTNR1AMTNR1BCYP2C19HIF1A | |
| SCHEMBL24952134 | 0.84 | TLR2 (0.39) | L3MBTL1MTNR1AMTNR1BCYP2C19HIF1A | |
| SCHEMBL17361242 | 0.82 | ALDH1A1 (0.51) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| Bromide SCHEMBL28529432 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL1669392 | 0.80 | CYP2C19 (0.39) | MTNR1AMTNR1BCYP2C19HIF1AALDH1A1 | |
| SCHEMBL63753 | 0.79 | CYP4F2 (0.50) | L3MBTL1CYP2C19ALDH1A1PTPN1 | |
| SCHEMBL22481266 | 0.78 | ALDH1A1 (0.53) | HDAC8L3MBTL1ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180134674-A1 | MAGL INHIBITORS | H. LUNDBECK A/S (DK) | 2018-05-17 | — | — | US | disclosed |
| US-20180134674-A1 | MAGL INHIBITORS | H. LUNDBECK A/S (DK) | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180134674-A1 | MAGL INHIBITORS | MAG, MAGI3, MGLL | HDAC8 2005/4885L3MBTL1 2479/4885MTNR1A 2310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.