Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PTPRC | P08575 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20151858 | 0.90 | HDAC8 (0.40) | MTNR1AMTNR1BCYP2C19HIF1ACA12 | |
| Bromide SCHEMBL28950639 | 0.89 | HDAC8 (0.39) | MTNR1AMTNR1BCYP2C19HIF1ACA12 | |
| SCHEMBL24951291 | 0.86 | TLR2 (0.39) | MTNR1AMTNR1BCYP2C19HIF1ACA12 | |
| SCHEMBL24952134 | 0.86 | TLR2 (0.39) | MTNR1AMTNR1BCYP2C19HIF1ACA12 | |
| SCHEMBL1669392 | 0.83 | CYP2C19 (0.39) | MTNR1AMTNR1BCYP2C19HIF1ACA12 | |
| SCHEMBL24952223 | 0.81 | LTA4H (0.38) | L3MBTL1 | |
| SCHEMBL9524467 | 0.81 | ALDH1A1 (0.50) | CYP2C19CA12CA7CA14ALDH1A1 | |
| SCHEMBL17777240 | 0.79 | ALDH1A1 (0.36) | CYP2C19HIF1AALDH1A1KDM4EMAPT | |
| SCHEMBL9466644 | 0.78 | SMN1; SMN2 (0.50) | CYP2C19ALDH1A1PTPN1TSHRL3MBTL1 | |
| SCHEMBL409786 | 0.77 | HSD11B1 (0.43) | CYP2C19HIF1AALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113135836-A | Preparation method of Sacubitril calcium salt | 鲁南制药集团股份有限公司 | 2021-07-20 | — | — | CN | claimed |
| CN-113135836-A | Preparation method of Sacubitril calcium salt | 鲁南制药集团股份有限公司 | 2021-07-20 | — | — | CN | disclosed |