SCHEMBL24958263

SCHEMBL24958263

COc1c(-c2ncccc2N)ccc2ccc(Cl)cc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.43
CCR9 P51686 2/20 0.43
G6PD P11413 1/20 0.39
NR4A2 P43354 3/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
MAT2A P31153 1/20 0.36
CYP3A4 P08684 2/20 0.36
CYP17A1 P05093 1/20 0.36
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36
S100A4 P26447 1/20 0.35
HSP90AA1 P07900 1/20 0.35
HSP90AB1 P08238 1/20 0.35
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 2/20 0.35
HPGD P15428 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
GAK O14976 1/20 0.34
RIPK2 O43353 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25470063 0.83 HSD11B1 (0.47) HSD11B1G6PDNR4A2L3MBTL1CYP3A4
SCHEMBL3663018 0.77 ALDH1A1 (0.49) CCR9G6PDL3MBTL1KDM4EALDH1A1
SCHEMBL25469987 0.76 G6PD (0.44) HSD11B1CCR9G6PDNR4A2L3MBTL1
SCHEMBL5205652 0.74 CCR9 (0.45) CCR9NR4A2L3MBTL1CYP3A4HSP90AA1
SCHEMBL31606910 0.74 CCR9 (0.45) CCR9NR4A2L3MBTL1CYP3A4HSP90AA1
SCHEMBL12303867 0.72 CCR9 (0.44) CCR9NR4A2CYP3A4S100A4KDM4E
SCHEMBL28410071 0.71 MGAM (0.49) G6PDL3MBTL1S100A4KDM4EALDH1A1
SCHEMBL24958400 0.68 MAPT (0.43) HSD11B1G6PDNR4A2CYP3A4CYP17A1
SCHEMBL28410115 0.67 PDE2A (0.51) G6PDCYP3A4KDM4EALDH1A1HPGD
SCHEMBL2713912 0.67 S100A4 (0.49) L3MBTL1S100A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023287252-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-01-19 WO disclosed