Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 4/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29159912 | 0.78 | RXRA (0.32) | RXRAGRIN1GRIN2B | |
| SCHEMBL24958754 | 0.78 | HTR7 (0.40) | TRPM5 | |
| SCHEMBL30028670 | 0.78 | HTR7 (0.40) | TRPM5 | |
| SCHEMBL30028557 | 0.77 | TRPM5 (0.36) | TRPM5RXRAGRIN1GRIN2B | |
| SCHEMBL24958966 | 0.77 | TRPM5 (0.36) | TRPM5RXRAGRIN1GRIN2B | |
| SCHEMBL24958825 | 0.76 | TRPM5 (0.36) | TRPM5 | |
| SCHEMBL30027743 | 0.76 | TRPM5 (0.36) | TRPM5 | |
| SCHEMBL24956444 | 0.76 | MCHR1 (0.36) | RXRAGRIN1GRIN2B | |
| SCHEMBL30679589 | 0.73 | LMNA (0.38) | — | |
| SCHEMBL26974530 | 0.71 | MAOB (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230021705-A1 | GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230021705-A1 | GLP-1R MODULATING COMPOUNDS | GLP1R, GIPR, GPR119 | TRPM5 1457/4885RXRA 1072/4885GRIN1 1159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.