Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 7/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24960657 | 0.80 | REN (0.39) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL24960646 | 0.80 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1KDM4EPKM | |
| SCHEMBL2060918 | 0.79 | L3MBTL1 (0.45) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL2061703 | 0.72 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL2205214 | 0.70 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL6287541 | 0.70 | PDE4A (0.40) | HDAC1HDAC6 | |
| SCHEMBL24960644 | 0.70 | MEN1 (0.50) | MEN1KMT2ATSHRALDH1A1KDM4E | |
| SCHEMBL16834135 | 0.70 | IRAK4 (0.57) | — | |
| SCHEMBL21468535 | 0.69 | S100B (0.38) | MEN1KMT2ATSHRALDH1A1MAPT | |
| SCHEMBL27580531 | 0.69 | POLB (0.37) | ALDH1A1HDAC1HDAC6GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026840-A1 | COMPOUND USED AS EGFR KINASE INHIBITOR AND USE THEREOF | TYK MEDICINES, INC. (CN) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026840-A1 | COMPOUND USED AS EGFR KINASE INHIBITOR AND USE THEREOF | EGFR, ERBB2, ERBB4 | CHRM2 4639/4885CHRM3 4169/4885CHRM4 4511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.